Biomedical subjects

A Cretti

Publications and source records attributed to A Cretti.

At least 19 recordsLinked to original sources

PubMed1994

[Influence of evening primrose oil on blood pressure and the pressor response to angiotensin II in pregnant and non-pregnant rabbits].

Evening primrose oil was given through a intragastric catheter in dose of 50 mg/kg day for 10 days to pregnant (8 animals) and nonpregnant (8 animals) rabbits. Control groups contained 8 pregnant and 8 nonpregnant animals. In the acute experiment we estimated directly (intraarterially) basal blood pressure and pressor response to angiotensin II (A II). The systolic and diastolic response to A II was significantly lower in pregnant rabbits which received evening primrose oil compared to control group. No significant effect was found in the nonpregnant groups. Basal (before A II) systolic and diastolic blood pressure did not differ between the treated and untreated subject in each group.

Angiotensin II↗

PubMed1993

[Effect of aminophylline on frequency of blood flow in utero-placental and fetal circulation, on arterial blood pressure and on cardiotocography].

Aminophylline was given (125 mg i.v.) in 24 cases with fetal hypotrophy. Blood flow was measured (Doppler technique) before aminophylline injection, 30 min. and 3-4 hours after. Blood pressure was monitored continuously, CTG was performed many times before and after administration of aminophylline. After administration of aminophylline diastolic blood pressure decreased during 3-4 hours and blood flow in the arcuate artery increased. There were no changes in the blood flow in the umbilical artery and fetal aorta after administration of aminophylline. We didn't observe any changes in CTG before and after administration of aminophylline.

Aminophylline↗

PubMed1992

[EPH gestosis or hypertension induced by pregnancy?].

The use of the term "pregnancy induced hypertension" is connected with the use of diagnostic criteria and classification to which this term belongs. These diagnostic criteria have important disadvantages: 1) only diastolic blood pressure is taken into account, 2) oedema is not taken into account, 3) there are only two severity grades, based only on the diastolic blood pressure, 4) "eclampsia imminens" does not exist, 5) "preeclampsia" is when there is elevated diastolic blood pressure and proteinuria, even of low severity both, other symptoms are not taking into account. The applying of such diagnostic criteria can contribute to inadequate management.

Diagnosis, Differential↗

PubMed1989

[3 classifications of gestosis].

Three classifications: of the American College of Obstetricians and Gynecologists (ACOG), of the Organization of Gestosis (OG) and of the International Society for Study of Hypertension in Pregnancy (ISSHP) differ among one another in some essential points. According to ACOG the term "preeclampsia" means a state with hypertension and albuminuria or edema, according to ISSHP--hypertension and albuminuria. This may lead to serious misunderstanding as many obstetricians use this term to identify a directly threatening eclampsia attack. But the two classifications do not provide a term for such a condition whereas according to OG this state is identified as threatening eclampsia. The OG and ACOG classifications give a classifications according to the progression of the disease, the ISSHP does not give such a classification. ISSHP does not consider edema as a symptom, ACOG takes it into consideration if it is accompanied by hypertension according to OG the very edema not subsiding after relaxation is enough to diagnose gestosis E. ISSHP has introduced the term "hypertension in pregnancy", but also includes one-symptom form "pregnancy albuminuria" not accompanied by hypertension. Such terms suggest lack of etiological relation between those forms, which has not however been proved. The names of one-symptom forms according to OG "gestosis H" and "gestosis P" do not impose such a relation (it is a classification according to symptoms), but they do not exclude it. Contrary to ACOG and OG, ISSHP gives the level of diastolic blood pressure only.

Congresses as Topic↗

PubMed1989

[Differences in the treatment of EPH gestosis between leading clinics and average hospitals].

157 hospitals from Poland with average number of deliveries 294,457 per year answered the questionnaires. In this paper some selected points of the answers are presented; on this basis the treatment of EPH gestosis in average hospitals (a.h.) is compared with the treatment in highly specialized, leading hospitals (l.h.). Similarly as in l.h. the fluid intake in 44% a.h. is not limited but the exact volume of fluid is rarely settled. Similarly to l.h. the salt intake in majority of a.h. is not limited, hydrazinophtalazin, magnesium, diazepam, dextrane and mannitol are widely used. In contrast to l.h. reserpin is still used in 53% of a.h., long-acting barbiturates in 17%, saluretics in 52%, but methyldopa and betablockers rarely (16% and 13%).

Antihypertensive Agents↗

PubMed1989

[Comparison of the effect of Lasolvan and betamethasone on lung maturity of fetal rabbits].

8 rabbits received Lasolvan i.v. on day 25, 26 and 27 of pregnancy. 8 rabbits received betamethasone i.m. on 26th and 27th day of pregnancy. The control group received 0.9% NaCl. On day 28 of pregnancy the caesarean section was carried out, the newborn rabbits killed after 45 minutes. In their lungs the lecithin contents was significantly higher in the Lasolvan group than in the betamethasone group and control group, but in the betamethasone group not significantly higher than in the control group. Betamethasone caused in the fetuses the lowering of the body weight, of the wet weight of lungs, of the dry weight lungs and the increase of the pulmonary fluid contents. Lasolvan had no such undiserable effect.

Ambroxol↗

PubMed1989

[Diagnosis and treatment of EPH gestosis at 157 Polish hospitals].

The average yearly number of deliveries in the 157 hospitals amounts to 294.457. The answers are accompanied by the numbers of hospitals which responded positively to a given question (in per cents). One symptom is enough to diagnose gestosis (90), only edema (82), on edema taken into consideration (3.8). Threshold values: RR 140/90 (68), V Korotkov phase (76), IV phase (21), albuminuria 0.1% (17), 0.2% (15), 0.3% (24), 0.5% (29). Gestosis index (77). Premature termination of pregnancy in serious gestosis often (33), almost always (32), always (21). In eclampsia secondary Cesarean section (46), primary (7), primary when fetus threatened (43). Liquids limited (42), liquids not limited (44), salt limited (73), intensively (12), salt not limited (12). Antihypertensives: hydrazinophtalazine (75), reserpine (53), alphamethyldopa (16), betablockers (13), ganglioplegics (7), diazoxide (1). Others: heparin (7), bufenin (4), other betamimetics (10). In eclampsia MgSO4 (91), benzodiazepins (65), phenothiazines (41), barbiturates (41), chloromethiasol (8), suprameningeal anesthesia (5), dextran (46), albumins (39), saluretics (49). Glycocorticoids when premature delivery in gestosis (56).

Antihypertensive Agents↗

PubMed1986