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Biomedical subjects

A Csermely

Publications and source records attributed to A Csermely.

12 recordsLinked to original sources
PubMed1986

Primary tumours of the liver: a review of 249 cases.

A total of 249 primary liver tumours was found in a 12-year necropsy and biopsy material. The majority of cases were liver carcinomas underlying liver cirrhosis, but several rare types were also observed. Histological classification, liver tissue changes around the tumours as well as the electron microscopic features of the tumours are discussed. Around the tumours three different types of dysplasia were noted and it is considered important to carry out further investigations to establish whether or not they are genuine precancerous conditions.

Autopsy↗
PubMed1981

[Electron microscopy of colonic polyps. II. Leuchtenberg's inclusion bodies].

Characteristic features of Leuchtenberger's inclusion bodies of adenomatous, adenopapillary and papillary polyps of the colon were studied by electron microscope. Authors believe that in the development of intracellular inclusion bodies focal degradation of the cytoplasma, of intercellular inclusion bodies, strangulation of certain areas of it may play a role. It is assumed that the development of inclusion bodies is a result of impairment of the cell membrane of proliferating, undifferentiated epithelial cells of the colonic mucosa. Increasing frequency of inclusion bodies in polyps undergoing malignant transformation seems to be an important morphologic feature.

Colonic Neoplasms↗
PubMed1981

[Electron microscopy of colonic polyps. I. Comparative study of epithelial cells from adenomatous and adenopapillary polyps].

Ultrastructural characteristics of premalignant epithelial dysplasia were studied electronmicroscopically by comparing epithelial cells of adenomatous- and adenopapillary polyps. In adenomatous polyps the rate of absorptive and goblet cells, their electron microscopic appearance did not differ from those of the normal colonic mucosa. In dysplastic areas of adenopapillary polyps severe proliferation of undifferentiated epithelial cells and disturbance of the maturation of absorptive and goblet cells was found. Severe damage to the cell membrane, atypical vacuola and dense bodies in the apical areas of absorptive cells were also seen. An abundance of Leuchtenberger's inclusion bodies as an important sign of the malignant transformation have occurred.

Colonic Neoplasms↗
PubMed1975

[Light and electron microscopic study of melanosis coli].

The authors describe the results of light- and electronmicroscopic investigation of the colonic mucosa in melanosis, occurring at a 35 years old male patient. In the tunica propria mucosae pigment storage macrophages described histologically can be recognized as well by the aid of electron microscope. In contrast to the light-microscopic picture, electronmicroscopically separation of the epithelial cells of the mucosa, accumulation of foreign material in the enlarged intercellular spaces, accumulation of granular-fibrillar matrix in the tunica propria and presence of plasma cells with increased secretory activity can be revealed. It is assumed, that separation of epithelial cells of the mucosa goes with the disturbance of the absorptive function. It can not be excluded, that electronmicroscopically revealed lesions of the coolnic musoca aggravate the severe obstipation. For this reason early diagnosis of the melanosis coli and ceasing the medication with athranol-glycosida-containing laxatives are very important.

Adult↗