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Biomedical subjects

A Cubero

Publications and source records attributed to A Cubero.

22 records · Page 2Linked to original sources
PubMed1982

[Effect of hydrogen peroxide on lipolysis and glucose metabolism in isolated rat adipocytes].

Rat fat cells show a high ability to eliminate H2O2, exogenously added or produced by the glucose/glucose oxidase system. The disappearance of H2O2 is a function of both time and the number of cells in the incubation medium. H2O2, like insulin, has been found to be antilipolytic even in the absence of glucose in the medium. Treatment of fat cells with ditio-(bis)-nitrobenzoic acid abolished this antilipolytic ability. H2O2 stimulated the hexose monophosphate shunt, and fatty acids and glicerides glycerol synthesis in rat fat cells. Flux through the hexose monophosphate shunt would then be a result of the demand for NADPH, for the fatty acids synthesis. These findings indicate that peroxidase can mimic the actions of insulin on glucose utilization and lipolysis.

Adipose Tissue↗
PubMedDate not supplied

[Epileptic crisis and multiple sclerosis: anatomo-clinical correlation].

INTRODUCTION: The prevalence of epilepsy in multiple sclerosis (MS) is low and the occurrence of an epileptic seizure as a first sign of this illness is even more infrequent. The relationship between both these illnesses is not clear; as epilepsy is a common condition, a coincidental association only could exist between the two diseases. OBJECTIVE: To establish a nexus of causality between epilepsy an MS. Clinical case. We present one case of epileptic seizures as the first manifestation of MS. The patient was a woman of 25 years old. The only result of the clinical examination was a right homonymous inferior cuadrantanopsy. The patient presented a high Tibbling index, lesions of demyelination in the subcortical occipital region and semioval centrum in the MRI and a pathological electroencephalogram; also, the visual and auditory evoked potential latency were delayed. CONCLUSIONS: We related he results of the neuroimaging, the clinical examination and the complementary tests of the patient. The appears to be a causal association between epilepsy and MS.

Adult↗
PubMedDate not supplied

[Recurrence of meningoencephalitis induced by cotrimoxazole].

Although infrequent, one of the etiological causes of aseptic meningoencephalitis is drug-induced. In our patient, two cases of meningocephalitis took place over a period of six years, together with a meningismus following consumption of trimetroprim-sulphametoxazol (cotrimoxazol). Features of the cases were mental confusion, fever, alterations in the CSF and a benign clinical course, with a high degree of doubt regarding diagnosis, given the similarity of anomalies in the CSF to those present in partially treated bacterian meningitis.

Anti-Bacterial Agents↗