[Endocrine exploration of pregnancy in clinical practice: myth or reality?].
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Biomedical subjects
Publications and source records attributed to A Curchod.
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The clinical features and the ovary biopsy findings of two cases of ovarian hypoplasia are presented. Both patients, 20 and 34 years of age, complained of primary amenorrhea. One patient presented growth retardation with genital and breast infantilism. The other patient, who received substitutive estrogen therapy, displayed normal adult secondary sexual characteristics. The chromosomal karyotype was 46,XX in both patients. The internal genital organs were hypoplastic. In the ovaries, the follicular maturation did not go beyond the secondary follicles which underwent atresia with a strange process of calcification beginning in the ova. The etiologic factors of this phenomenon are unknown. The authors found only one analogous case in the literature.
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Cells of fetal origin have been searched for in the peripheral blood of mothers following delivery of a boy, using mepacrine fluorescence of the Y chromosome. In a series of 62 women such cells have been found for approximately two years in more than half of cases. Their number decreases thereafter but in some instances Y chromosome-bearing cells have been observed 5 years after delivery.
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