Biomedical subjects
Publications and source records attributed to A Cyrkowicz.
The complete, spontaneous uterus eversion in 23 years old primipara in the third stage of normal labour is described. After detachement of placenta the uterus was repositioned manually. To make the procedure easier the drip infusion of fenoterol was applied.
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The posterior pituitary lobe of male rats under urethane anaesthesia was incubated in situ. The pituitary gland was exposed by thr transpharyngeal apprach. The posterior lobe remained in neural and partial vascular connexion with the hypothalamus, whereas the anterior lobe was entirely remobed. Incubation fluid was collected and its melanophore-stimulating activity was assayed in hypophysectomized frogs. No effect was observed after the i.v. injection of 1 ml 120 muM-NaC1 with 60 muM-CaC12 or isotonic NcC1 solution. Hypertonic solutions of 5% NaC1 and 25% glucose injected intravenously to the limit of 0-5% of the body weight, transiently enhanced the release of MSH from the posterior pituitary lobe by 66% (significant) and 15% (not significant) respectively. Intracarotid injection of 0-3 ml 5% NaC1 solution resulted in the highest increase (95%) of MSH release.
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After removal of the whole pituitary gland in the rat, intravenous injection of 5% NaCl solution (0.5% of body weight) had no effect on MSH release from the washed hypothalamic end of the cut pituitary stalk and the ventral surface of the median eminence.
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Release of oxytocin from the rat posterior pituitary lobe incubated in situ and from the hypothalamic end of the cut pituitary stalk. Acta Physiol. Pol., 1978, 29 (2):97--105. Using the method of incubation in situ of the posterior pituitary lobe and washing the hypothalamic end of the divided pituitary stalk the activity of neurosecretory neurons was investigated directly. The oxytocic activity of the fluid incubating in situ the posterior pituitary lobe or washing the hypothalamic end of the cut pituitary stalk was determined on the rat myometrium. The oxytocic activity disappeared from this fluid after inactivation with sodium thioglycolate. The samples of the fluid incubating the posterior pituitary lobe obtained at 30 min intervals showed alternatingly increased or decreased oxytocic activity. In the fluid washing the cut pituitary stalk the activity was highest from 31 to 60 minutes after division of the stalk.