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Biomedical subjects

A D Andreev

Publications and source records attributed to A D Andreev.

5 recordsLinked to original sources

[Initial experience with laparoscopic appendectomy].

On the basis of analysis of their personal experience and the literature data, the authors claim that appendectomy under control of a laparoscope is an alternative to the traditional operation. Laparoscopic appendectomy was conducted in patients with acute and chronic appendicitis. The indication for appendectomy in chronic form of the disease is determined by the results of complete clinical examination and laparoscopic inspection of the region of the right iliac fossa, which is undertaken before each operative intervention. The authors performed laparoscopic appendectomy with the use of a monitor which made it possible for the operating team to watch the operation. The base of the process was ligated with an endoligature or compressed with clips, and then cutoff by means of high frequency current. The stump of the process was not buried in the cupula of the cecum. Laparoscopic appendectomy for chronic appendicitis was performed, as a rule, as a simultaneous intervention in laparoscopic cholecystectomy or operations undertaken for other diseases. The authors did not encounter in the postoperative period any complications associated with appendectomy. The postoperative period was somewhat easier than after the traditional intervention. The motor activity of the patients was completely restored as early as the second-third day. Experience shows competence of such operations.

Acute Disease

[Models of cell recovery during fractionated and prolongated irradiation].

On the basis of the previously proposed general model for cell recovery from radiation damage, and the ideas of the effective dose reduction, the models have been developed for the radiation regimes which are considered to be most interesting for application. There was a satisfactory agreement between the models and the experimental data. The questions of application of the models proposed are discussed.

Animals

[Modeling the processes of cell recovery from radiation injury and the effective dose reduction principle. Model of postradiation recovery with a finite number of recovery channels].

Using the effective dose reduction principle for the description of the postirradiation recovery a mathematical model has been developed with the definite number of recovery channels in a cell. It was established that the number of recovery channels in Megri 139-B yeast cells was of the order of 10. The model may be applied for co-ordination of studies in the repair of radiation-induced lesions in a DNA molecule and in the postirradiation survival of exposed cells.

Cells