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Biomedical subjects

A D Belov

Publications and source records attributed to A D Belov.

9 recordsLinked to original sources
PubMedDate not supplied

DNA polymerase activity of lymphocyte nuclei of cattle lymph in the normal state and in lympholeukemia.

A comparative study wad made of the DNA polymerase activity of lymphocyte nuclei of cattle lymph in the normal state and in lympholeukemia. No significant differences were found in the specific DNA polymerase activity of the nuclei of normal and leukemic lymphocytes, both in the absence and in the presence of exogenous "activated" DNAs. The DNA polymerase activity of both types of nuclei was a maximum at pH 7.8 and a Mg2+ concentration of 4--6 mM. The DNA polymerase activities of lymphocyte nuclei of the lymph of healthy and leukemic animals did not differ in sensitivity to the inhibiting action of actinomycin D and in thermal stability. It was concluded that in cattle lympholeukemia, there are no significant changes in the DNA polymerase system of lymph lymphocyte nuclei.

Animals↗
PubMedDate not supplied

Life span of lymphocytes in cattle in the norm and during lymphatic leukemia.

Comparison was made of the rate of in vivo elimination from blood and organs of cattle of lymphocytes labeled with 3H-thymidine in the course of seven days in the norm and during lymphatic leukemia. Significant delay in the elimination of labeled lymphocytes, and especially of lymphocyte precursors, from the blood, spleen, and lymph glands of the animal was established in the stage of lymphatic leukemia that was examined.

Animals↗
PubMedDate not supplied

[Contents of general, bound and free cortisol in sheep blood during different periods of acute radiation sickness].

The hypothalamic-hypophyseal-cortical multifetal sheep system reaction was examined to respond the sharp single action X-rays dosed 0.96 and 3.84 Gr. The primary irradiation answer was accompanied by expressed hypercorticoidism, which essentially increased with irradiation dose rising and followed the induction of CRF-hypothalamic activity. The secondary sheep hypercorticoidism preceded the clinico-hematomancy and depended on irradiation dose. Hypercorticoidism-2 resulted in blood free bioactive cortisol content increasing. The compensative decrease of named system activity favoured to beam illness outcome. It the prognosis was poor the free and reached its peek before animal death. These data can be used as a test for beam illness outcome prognosis.

Acute Disease↗
PubMedDate not supplied

[Evaluation of biological sequelae for cattle in the zone of the Chernobyl accident].

The influence of Chernobyl NPP outburst on cattle from farms in Russia and Belorussia was examined since 1988 to 1996. Changes in the level of thyroid hormones and imbalance in cAMP/cGMP ratio with increased cAMP concentration in blood were found. The content of cAMP and E, F2a prostaglandins was varied because of the disturbances in the rate of their metabolism. Two critical periods of pregnancy in cows were revealed. In the first half of pregnancy (the 4th-5th month) disorders in thyroid prevailed. In the second half (7th-9th month) changes in testosterone, progesterone, estradiol and estriol concentration were the most actual.

Animals↗