PubMed Health⌕ Search

Biomedical subjects

A D Buncio

Publications and source records attributed to A D Buncio.

2 recordsLinked to original sources
PubMed1988

Peripheral leucocyte count and longitudinal decline in lung function.

A six year follow up study of 750 aluminium smelter workers was undertaken to evaluate the relationship between the leucocyte count at the start of the study and the rate of decline in lung function. An inverse relationship between the leucocyte count and the forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) was present cross sectionally irrespective of cigarette smoking habit. The initial leucocyte count was also significantly related to the mean annual decline in FEV1 in smokers (p = 0.04) but not in former smokers or those who had never smoked. These observations suggest that the leucocyte count is a factor influencing the annual decline in FEV1 in smokers.

Adult↗
PubMed1984

Leukocyte count, smoking, and lung function.

The interrelation between leukocyte count, cigarette smoking, and pulmonary function results was examined in two work populations: 1,826 white male workers in a pulp and paper mill and 1,620 white male workers in an aluminum smelter in British Columbia. These workers took part in epidemiologic health studies that consisted of a medical-occupational questionnaire, spirometric measurements, and leukocyte count. Measurements of the air contaminants in the work environment were also carried out simultaneously by personal and area sampling. No significant increase in the prevalence of respiratory symptoms and lung function abnormalities was found between the exposed and nonexposed workers in each work population. Similarly, no difference in leukocyte count was found between exposed and nonexposed workers. Leukocyte count was found to be significantly higher among current smokers than nonsmokers and former smokers in each population. In both populations, there was an inverse correlation between leukocyte count and one-second forced expiratory volume and forced vital capacity of the workers irrespective of the smoking habit. This finding suggests that the leukocyte response to external stimuli may be another determinant of lung function measurements.

Adult↗