BACKGROUND: Despite the important association of central adiposity and cardiovascular and other risk factors, there are only three reported values for directly weighed visceral adipose tissue (AT). All other reported values are based on medical imaging techniques. OBJECTIVE: The study aimed to investigate the relationships between visceral, trunk and total AT weights in older men and women. METHODS: Data was obtained from the combination of two studies involving the complete dissection of 15 male and 16 female cadavers (age range 55-94 years) and allowed for compartmentation into skin, AT, muscle, bone and a residual component, divided over six body segments: head, trunk, legs and arms. Visceral AT was separated from trunk subcutaneous AT. All tissues were weighed. RESULTS: Visceral AT weights ranged from 0.3 to 5.8 kg. Mean values were 3.00 +/- 1.52 kg (mean +/- SE) for the men and 3.24 +/- 1.67 kg for the women. These were not significantly different (p = 0.68), but visceral AT weight, expressed as a percentage of total body AT weight was significantly greater (p = 0.02) in the men (16.8 +/- 5.4%) than in the women (12.9 +/- 3.5%). Correlations between visceral AT weight and the weight of subcutaneous AT of the trunk were highly significant (men, r = 0.70, women, r = 0.81, p < 0.005), with similar slopes for the two sexes. The correlation coefficients of visceral with total body AT weights were even greater (men, r = 0.83 and women, r = 0.96, p < 0.0001). CONCLUSIONS: In this sample of older Belgians, visceral AT is strongly related to total body adiposity, corresponding to an increment of about 200 g of visceral AT for every kilogram of total AT in men and about 180 g in women. Because of this relationship, techniques such as skinfold calipers and ultrasound for assessing whole body fatness from measurement of only the subcutaneous layer are thus able to account for visceral adiposity.

Adipose Tissue↗

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Bone mineral density and adipose tissue distribution in young women: relationship to smoking status.

Interrelationships between anthropometric variables and bone mineral density (BMD) may allow simple and inexpensive identification of those at risk for low bone density and osteoporosis. Risk appraisal is particularly important in young women, as lifestyle modifications may slow the rate of bone loss through adulthood and decrease the risk of osteoporosis later in life. Though weight, height and body mass index are frequently assessed in relation to bone, adipose tissue distribution has rarely been considered. Smoking is associated with low bone density and abdominally localized adipose tissue. The relationship between smoking, adipose tissue distribution and BMD in women has not been examined. Regional and whole-body BMD were assessed by dual-energy X-ray absorptiometry, and adipose tissue distribution using the anthropometric indicator, waist-to-hip girth ratio (WHR), in 52 women (25 smokers, and 27 nonsmokers) aged 20-35 years. There were significant (p < 0.05) positive correlations between WHR and BMD for smokers and nonsmokers separately (r = 0.44-0.57), and for the sample overall (r = 0.30-0.51). Most relationships remained significant after adjustment for weight. Smokers did not differ significantly from nonsmokers in relationships between WHR and BMD. The results indicate a positive relationship between BMD and abdominal relative to gluteal-femoral adiposity. This relationship is independent of smoking status. The biological determinants underlying a relationship between BMD and WHR require consideration before inferences regarding BMD can reasonably be considered on the basis of WHR.

Adipose Tissue↗