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Biomedical subjects

A D McLachlin

Publications and source records attributed to A D McLachlin.

At least 19 recordsLinked to original sources
PubMed1976

Delayed primary closure of the skin and subcutaneous tissue in abdominal surgery.

Infection-prone abdominal incisions in 143 patients were managed by delayed primary closure of the skin and subcutaneous tissue of the abdominal wall. The overall wound infection rate was 1.4% and the rate for 74 open, large bowel operations was 2.7%. These rates compare favourably with a rate of 3.1% for clean inguinal hernia repairs done by the same surgical team over the same period. Delayed primary closure, carried out on the ward 3 days after operation, was simple, easy and did not prolong hospital stay. Its use is recommended in closing all abdominal wounds associated with a special risk of infection.

Abdomen↗
PubMed1976

Anterior anastomosis of the rectosigmoid colon: an experimental study.

Leakage in anastomoses below the peritoneal reflection after resection of the upper rectum and lower sigmoid colon has been studied in an experimental model in the dog. With blood alone or with blood and E. coli in the pelvis about the anastomosis, there was no significant increase in the frequency of leakage. With dead space about the anastomosis created by removal of pelvic fat and anterior tacking of the prostate and urinary bladder to the abdominal wall to simulate the human subject with a wide removal of intestine, mesentery, and pelvic fat for carcinoma, there was a high incidence of leakage. When the dead space about the anastomosis was filled with a pedicle graft of viable omentum, there was a significant decrease in the incidence of leakage. In this model dead space about the low anastomosis limiting contact with viable tissue that could adhere to, seal off, and finally revascularize the endangered intestine seemed to be a major cause of leakage. A pedicle graft of viable omentum that filled the dead space reduced the chance of leakage.

Animals↗