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Biomedical subjects

A D Romashchenko

Publications and source records attributed to A D Romashchenko.

At least 19 recordsLinked to original sources

[Effect of the water-soluble antioxidant hydroxypyridine-6 on the intensity of lipid peroxidation in eye tissues in experimental ophthalmic herpes].

Lipid peroxidation (LPO) in eye tissues of rabbits with experimental herpetic keratitis was evaluated from the malonic dialdehyde content and chemiluminescence intensity. It appeared that during the critical phase LPO sharply increased in all the tissues under study and in anterior chamber humor. After administration of the synthetic water-soluble antioxidant, hydroxypyridine-6 the subconjunctival content of malonic dialdehyde and chemiluminescence intensity approached normal values accompanied by positive therapeutic effect.

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[Immobilized streptokinase (streptodecase) in the treatment of traumatic intra-ocular hemorrhage].

Streptodecase was used in experiments and in clinical practice for treatment of intraocular traumatic hemorrhages. The enzyme, at a dose of 30,000-45,000 .un, did not exhibit any toxico-allergic effects on eye tissues and caused maximal lysis of the blood clot. 114 patients were treated with the enzymatic preparation and in 60% of the patients blood, liberated into vitreous body, was completely lysed.

Animals↗