Changing trends in shigellosis at a tertiary care centre.
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Drug Resistance, Bacterial↗
Biomedical subjects
A D Verma
Publications and source records attributed to A D Verma.
Flavobacterium meningitis.
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Bacterial Infections↗
Incidence of shigellosis and multi-drug resistant Shigellae: a 10 year study.
Between 1976 and 1985 a total of 12,709 faecal samples were cultured. From these samples 760 strains (6.0%) of Shigellae were isolated. Shigella flexneri was the commonest isolate (55%), followed by S. dysenteriae (29.7%). A total of 15.7% of children under 5 years of age were positive for Shigellae. The rate of isolation was lower during the winter months than in the summer months. Only 25 strains (3.3%) were sensitive to all five antibiotics tested. A total of 617 (81.2%) were resistant to three or more antibiotics (multi-drug resistant). The minimum inhibitory concentrations (MICs) of five drugs were calculated in 100 strains. Streptomycin showed an MIC of 25 micrograms ml-1 or less for only seven strains. MICs of chloramphenicol tetracycline and ampicillin were found to be as high as 100-1000 micrograms ml-1 for the majority of strains. Sulphonamide showed an MIC of 1000 micrograms ml-1 for 93 strains.
Anti-Bacterial Agents↗
Drug resistance in Salmonellae isolated at Chandigarh (India) during 1972-1978.
A total of 1316 strains of Salmonella belonging to 20 serotypes isolated at P.G.I. Chandigarh (India) were tested for drug resistance. Drug resistance was noticed in 494 (38.3%) of the strains; 194 (14.8%) of these strains were resistant to one drug, while 300 (23.5%) had multiple drug resistance. All isolated strains were sensitive to gentamicin, furazolidone and nalidixic acid. Resistance to streptomycin was observed in 233 (17.7%), chloramphenicol 197 (14,9%), tetracycline 293 (22.3%), ampicillin 428 (32.5%), kanamycin 206 (15.7%), neomycin 206 (15.7%) and sulphadiazine 215 (19.9%). Multiple drug resistance was most common in S. bareilly, S. typhimurium and S. anatum serotypes. Increase in incidence of drug resistance in Salmonellae has been noticed during 1972-1978.
Anti-Bacterial Agents↗