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Biomedical subjects

A Dachy

Publications and source records attributed to A Dachy.

At least 19 recordsLinked to original sources

[The Communauté française' eradication plan for measles, mumps and rubella].

The combined vaccine against measles, mumps and rubella provides an efficient tool for the elimination of these three diseases in a community. In the French Community of Belgium the MMR vaccine is commercially available since 1984 and was officially included in the immunization schedule in 1985. The present coverage rate is estimated at 60% of the children under 24 month. To improve the situation, the "Conseil Consultatif Communautaire de Prévention pour la Santé" of the French Community of Belgium has proposed a programme of MMR immunization promotion based on a coordinated mobilization of the various structures involved i.e. MCH organization, school medicine, general practitioners, pediatricians, Faculties of medicine and Health Administration. The programme has been adopted by the political authority and has started on February 1st 1989.

Belgium

[Periarteritis nodosa in children. Diagnostic difficulties in 2 cases].

Periarteritis nodosa is a rare multisystemic disease whose diagnosis is difficult: diagnostic approach by biopsies in various involved organs is of poor efficacy; abdominal selective angiography yields a precise diagnosis in 50 to 60 of the studied cases as far as the celiac, mesenteric and renal circulations are investigated selectively. Digitalized intravenous angiography (DIVA) carried out in two patients of 9 and 13 years of age allowed to demonstrate aneurysm formations in hepatic, renal and cerebral circulations. Its true efficacy in the diagnosis of periarteritis nodosa of children remains to be determined.

Adolescent

Mortality in meningococcal disease in Belgium.

A survey of children admitted with meningococcal disease to 53 paediatric units in Belgium between 1975 and 1979 was made in order to assess the case mortality rate (CMR) and to identify risk factors associated with death. A total of 309 cases (226 bacteriologically confirmed and 83 unconfirmed) was recorded. The overall CMR was 6.1 per cent. It was 4.4 for bacteriologically confirmed cases and 10.8 for unconfirmed cases. The CMR was higher for septicaemia without meningitis (22.2 per cent) than for meningitis with or without signs of septicaemia (3.4 per cent). The risk of death was not related to the sex or nationality of the patients. Age was a major determinant of the CMR, independently of the clinical picture. The highest risk of death was in children under one year of age. Poor socio-economic conditions were a significant risk factor. Failure to recognise the severity of the disease by some poorly educated mothers, and the admission of the patient to a hospital lacking adequate facilities for managing severely affected children, were the two significant causes of delay of adequate treatment.

Adolescent

Meningococcal disease in Belgium. Secondary attack rate among household, day-care nursery and pre-elementary school contacts.

During a recrudescence of meningococcal disease mainly due to serogroup B, 1913 notified cases were investigated in Belgium from 1971 to 1976. From 1971 to 1973, 76 secondary cases were reported out of a total of 1455 cases (5.2 per cent); and from 1974 to 1976, nine secondary cases were reported of a total of 458 cases (2.0 per cent). Seventy per cent of the secondary cases occurred within seven days after the Index case. The 4.7 per cent fatality rate among secondary cases was lower than the 9.8 per cent fatality rate among primary cases. The estimated secondary attack rate was 685 per 100 000 among household contacts, 404 per 100 000 among day-care nursery contacts and 77 per 100 000 among pre-elementary school contacts. These attack rates were significantly higher (P less than 0.001) than the incidence rates in the corresponding age-groups in the general community, indicating the need for prophylaxis in these contacts.

Adolescent

[Pediatric home care services in Belgium].

In 1970 a home care service for children was started by the committee for public assistance in Brussells with medical supervision from the department of paediatrics of the University. The main features are as follows: - It is exclusively paediatric and its aims are to shorten or avoid hospital admissions, or to provide medico-social support especially for the underpriveledged. - The medical supervision is undertaken by the family doctor (15% of cases) or by the physician in charge of the home care service with the help of specialists in the department of paediatrics in necessary. - Social workers, nurses and physiotherapists look after social problems, give nursing care and appropriate treatment. - The service has its own secretaries.

Belgium

Concentration of gentamicin in bronchial secretions of children with cystic fibrosis of tracheostomy. (Comparison between the intramuscular route, the endotracheal instillation and aerosolization).

The levels of gentamicin in blood and in secretions of the tracheobronchial tree were measured in 14 children (8 with cystic fibrosis and 6 with tracheostomy) in a cross over fashion after the administration of 40 mg of gentamicin by aerosol or by endotracheal injection. High levels of gentamicin (greater than 20 mug/ml) within the bronchial secretions were observed in 7 children after aerosolization and in 11 children after endotracheal instillation. Corresponding blood levels were low (less than 3 mug/ml) in all patients and no detectable levels were found in 10 children after aerosolization and in 6 children after endotracheal instillation. No significant differences were observed between children with cystic fibrosis and those with tracheostomy. Since intramuscular injection of gentamicin (a single dose of 1.5 mg/kg) resulted in low levels of gentamicin within the bronchial secretions (less than 2 mug/ml in 10 patients, among whom 4 had undetectable levels); it is concluded that the administration of an antibiotic such as gentamicin, directly to the trachea by endotracheal injection or by aerosolization might prove to be helpful when the infection is confined mainly to the tracheo-bronchial tree.

Adolescent