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Biomedical subjects

A Dana

Publications and source records attributed to A Dana.

At least 37 records · Page 2Linked to original sources

Metastatic cerebral choriocarcinoma coexistent with a viable pregnancy.

Gestational choriocarcinoma associated with a viable pregnancy is extremely rare, and such choriocarcinoma with metastases presenting during the pregnancy is even more exceptional. Metastases from this tumor may present in a variety of ways depending on the site of the metastatic lesion, and can be fatal before choriocarcinoma is even suspected. We describe a 32-year-old primigravida presenting at 31 weeks gestation with a grand mal seizure due to cerebral metastases secondary to gestational choriocarcinoma who was subsequently successfully treated with chemotherapy. To our knowledge this is the first reported case of choriocarcinoma presenting with signs due to cerebral metastases during pregnancy where both the mother and child survived. This paper emphasizes the need to consider metastatic choriocarcinoma in any gravid female who presents with unusual neurological signs because of the life-threatening nature of this potentially curable disease.

Adult↗

[Echography in pyelocaliceal tumors].

In a study of over 32 pyelocaliceal tumors greater than 1 cm in diameter, the authors review retrospectively the reports of the pyelographic and sonographic documents obtained in these patients before the definitive diagnosis was confirmed by the pathological examination. They observed that pyelography has a much greater diagnostic accuracy than does sonography: 31 confirmed (27) or suspected (4) tumors whereas only one tumor was overlooked (silent kidney) on pyelography and 12 diagnosed tumors, 15 overlooked and 5 diagnostic errors on ultrasonography. However, it should be noted that the results of ultrasonography are much better when the results of the intravenous pyelogram are known than when the latter is performed first. These results are supported by triple-blind re-reading of ultrasonographic documents of tumors of the excretory tract grouped with documents of normal kidneys presenting another disease of the sinus. The authors conclude that ultrasonography must be performed first whenever a tumor of the excretory tract is suspected (especially in case of hematuria) and that in this field, there are essentially two indications for ultrasonography: --To remove a stone (hyperechogenic with a cone of shadow) if there is a pyelocaliceal lacuna of unknown cause. --To establish that obstruction is due to a tumor, in the presence of a silent kidney.

Hematuria↗

[Ultrasonographic concept of the central prostate. Value of the endorectal approach].

In view of the difficulties involved in tissue characterisation of prostatic lesions by suprapubic and transrectal ultrasonography, the authors propose the concept of the central prostate in order to improve the possibility of histological diagnosis based on a topographical approach to ultrasound modifications. When the lesions are selectively situated in the central prostate, with clear distinction between the central prostate and the peripheral prostate, there is a low probability of a neoplastic lesion. However, the histological diagnosis must be extremely cautious and when a suspicious lesion is detected on ultrasonography, ultrasound guided aspiration biopsy may be required.

Adenoma↗

[Desmoid fibroma of the abdominal wall. Apropos of a case].

A case of desmoid fibroma of anterior abdominal wall, an exceptional benign tumor, is reported. Based on results of CT scan imaging of this lesion, differential diagnosis of other expansive processes of abdominal wall are discussed. This benign tumor is a potentially serious lesion due to its infiltrating character and the high incidence of recurrence. The need for total surgical excision is emphasized.

Abdominal Muscles↗

[Radiological studies in the preoperative diagnosis of cystic cystadenoma of the kidney].

Investigations in 7 patients with cystadenoma (5 cases) or cystadenocarcinoma (2 cases) of kidney included intravenous urography, ultrasonography, arteriography and in 4 cases, computed tomography imaging. All these examinations, and particularly ultrasound imaging, provided strongly suggestive evidence of the diagnosis, as seen on images as a single parenchymatous mass constituted of "cystic" formations separated by partitions of variable thickness. Possible differential diagnosis includes necrotic cancer, hydatid or blood-containing cysts. Unfortunately, these different imaging techniques fail to distinguish between thick wall cystadenoma and cystadenocarcinoma, positive diagnosis requiring histology. Preoperative recognition of cystadenoma allows initial conservative surgery to be performed, followed by secondary operation if histology reserves an unpleasant surprise.

Adult↗

[Lymphography and lymph node excision in bladder cancer. Apropos of a series].

The authors reviewed a series of 100 consecutive total cystectomies for carcinoma of the bladder, 78 with bilateral pelvic lymph node dissection and 43 with preoperative lymphography, attempting to determine the reliability of lymphography, to quantify the risk of lymphadenectomy and to assess the usefulness of lymphadenectomy when the nodes are involved. Routine reading of lymphography was associated with a level of accuracy of 68.7% an error rate of 10.8% and a level of uncertainty of 20.5%. Evaluating the results by number of patients rather than by the number of sides opacified by lymphography, the score was even lower: accuracy 60.5%, error 13.2%, doubt 26.3%. Strictly reviewing those cases where all necessary information was present in the record, initial routine reading of lymphographies gave 58% accuracy, 14% error, and 28% doubtful. Retrospective reading by one radiologist only gave much better results, but these did not correspond with the results obtained in everyday routine work. The number of complications related to lymphadenectomy appeared slight: amongst 78 operations, one lymphocoele, two cases of prolonged lymphatic discharge and three cases of oedema of the lower limbs. Of 14 patients with involved nodes, only three are living without recurrence and with follow-up periods which are as yet too short. All patients with involvement extending above the common iliac bifurcation died within a short time, as did all those with prostatic involvement. Comparing the data from their own series and the literature, the authors came to the following conclusions.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[Ultrasonographic appearance of renal cancer. Correlation with arteriographic and histopathologic findings in 45 cases (author's transl)].

Ultrasonographic, arteriographic, and histopathological findings were compared in 45 patients with histologically-confirmed renal cancer. Ultrasound images clearly demonstrate the presence of a mass possessing similar echographic characteristics to those of the renal parenchyma (isoechogenic forms). Images are rarely homogeneous and are usually of a heterogeneous nature, either diffuse or including anechogenic zones (heterogenic lacunar forms). This latter appearance is almost specific for tumor necrosis, but a diffuse heterogenic image may be observed with or without the presence of necrosis. Necrotic cancers, with limited peripheral vascularization, present few diagnostic difficulties during ultrasonographic examination: the appearance is that of a solid mass, isoechogenic in the present series, heterogeneous, and with or without anechogenic zones. No correlation exists between the degree of echographic image alterations and the importance of vascularization, poorly vascularized cancers, of particular histological types, demonstrating hypo or hyper-echogenic changes more frequently than typical adenocarcinomas.

Adult↗

[The echographic assessment of the size of normal pyelo-calyceal cavities. Accuracy and limits (author's transl)].

The authors studied using two echographies 90 kidneys in 53 patients free of known urinary tract pathology and not suffering from renal colic, the first immediately before intravenous urography (at a stage of relative fluid restriction) and the second before micturition (at a stage of higher urine output and filling of the bladder). Findings were as follows: - normal excretory cavities may be seen by echotomography, this being in contrast to a widely held view; - changes in the echographic appearance of the pyelocalyceal cavities may occur in the absence of any pathology merely as a result of changes in urine output. They draw attention to the possible errors inherent in echotomography performed alone. They emphasise the need, at least in the absence of renal insufficiency, to preceed any echography by intravenous urography.

Adolescent↗