PubMed Health⌕ Search

Biomedical subjects

A Date

Publications and source records attributed to A Date.

At least 19 recordsLinked to original sources
PubMed1988

Medical renal disease in the elderly in a southern Indian hospital.

A review of 85 patients aged 60 years or more, treated in a southern Indian hospital for conditions requiring renal biopsy, showed that diffuse poliferative glomerulonephritis was the most frequent diagnosis, being present in 24 cases of whom 11 had elevated serum streptococcal antibody titres. Infections were also important in 2 patients with amyloidosis secondary to tuberculosis, in 3 patients with acute tubular necrosis following infectious gastroenteritis and in a patient with acute pyaemic interstitial nephritis with septicaemia. Drugs including indigenous medicines were the other important cause of renal disease, being implicated in 11 cases.

Aged↗
PubMed1987

Systemic fungal infections in south Indian infants.

Systemic fungal infections were identified in 13 of 1468 necropsies of infants dying in the 1st year of life in a south Indian hospital. Candidiasis was present in 11 infants, most often as pneumonia or enteritis. Spread to other organs occurred in four cases. Intestinal candidiasis was associated with zygomycosis of the intestine in one infant and with aspergillosis of the lungs and intestine in another. One case of aspergillosis of the myocardium and one of gastric zygomycosis were also diagnosed. Septicaemia, broad spectrum antibiotic therapy, surgery and congenital abnormalities, including immune deficiencies, were important predisposing factors.

Aspergillosis↗
PubMed1987

Fungal and nocardial infections of the kidney.

This report describes 16 cases of candidiasis, seven of aspergillosis, four of mucormycosis, two of cryptococcosis and one of nocardiosis in which the kidney was involved. Characteristic patterns of renal tissue injury were seen in each of these infections. Candida and nocardia caused microabscesses in the cortex and medulla. Tissue destruction was minimal with candidiasis and when present was confined to the papillary tips and produced only mild impairment of renal function. Aspergillus and mucor invaded blood vessels resulting in thrombosis and extensive necrosis of cortical and medullary tissue and most patients had clinical and biochemical evidence of renal disease. Cryptococcosis caused no tissue reaction or clinically evident renal disease in the two immunosuppressed patients studied.

Adolescent↗
PubMed1987

Minimal-change nephrotic syndrome in adults treated with alternate-day steroids.

Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission at 16 weeks. Of the 54 patients, 8 (14.8%) had frequent relapses and 9 (16.6%) had infrequent relapses. No serious complications as a result of steroid therapy were encountered.

Adolescent↗
PubMed1987

Renal disease in adult Indians: a clinicopathological study of 2,827 patients.

Nephrotic syndrome was the commonest clinical presentation among 2827 consecutive adult Indian patients from whom adequate kidney biopsies were obtained for suspected renal disease. In 83 per cent of cases the nephrotic syndrome was due to minimal change disease, focal segmental glomerulosclerosis, mesangiocapillary glomerulonephritis, membranous usually secondary to tuberculosis or leprosy, was present in only 34 patients. Acute nephritis, the next most frequent clinical presentation, was due to diffuse endocapillary proliferative, crescentic or mesangial proliferative glomerulonephritis in 88 per cent of cases, almost half of whom had elevated serum streptococcal antibody titres. Eosinophilia showed a highly significant association with diffuse endocapillary proliferative and mesangiocapillary glomerulonephritis. Idiopathic IgA nephropathy was present in only 10, and antiglomerular basement membrane antibody disease in only one, of the 238 patients whose biopsies were studied by immunofluorescence. Complications of pregnancy accounted for 70 per cent of cases of cortical necrosis. Acute gastroenteritis, septicaemia, abortions, snake bite and allopathic and indigenous medicines were important causes of acute tubular necrosis.

Adolescent↗
PubMed1985

Hereditary chronic nephritis in India.

Forty-six patients from 23 Indian families with hereditary chronic nephritis (HCN) with or without Alport's syndrome are presented. The occurrence of this disease in diverse Indian races, communities and castes is now documented. Clinical and laboratory findings in these patients are similar to those reported from temperate regions.

Adolescent↗
PubMed1985

Renal lesions and other major findings in necropsies of 133 patients with leprosy.

A study of 133 necropsies on leprosy patients showed that renal disease, pyogenic infections, and tuberculosis were the most frequent causes of death. Major kidney lesions encountered included glomerulonephritis of different types, pyemic abscess, acute tubercular necrosis, amyloidosis, and chronic pyelonephritis. In many cases the renal lesions were secondary to infections in other organs. Case control studies are required to determine if the high prevalence of these diseases is related to leprosy, its complications, or its therapy, per se, or if it is a reflection of the disadvantaged and poor socioeconomic status of these patients.

Abscess↗