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Biomedical subjects

A De Coninck

Publications and source records attributed to A De Coninck.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Mediastinal tracheotomy in cervicofacial oncologic surgery. Contribution of the pectoralis major myocutaneous flap].

Four cases of anterior mediastinal tracheostomy with myocutaneous Pectoralis Major flap are described. Resection of the manubrium, clavicular heads and the cartilages of the first and second ribs is necessary. The use of myocutaneous Pectoralis Major flap give good functional results. No infection or hemorrhage of mediastinal great vessels occurred. The indications of Anterior mediastinal tracheostomy are discussed. Stomal and peristomal recurrences following laryngectomy for carcinoma represents the indication of choice. Stomal recurrences are difficult to treat and the prognostic is poor. Prevention of the stomal recurrences is discussed.

Aged↗
PubMed1984

[Personal experience with a myocutaneous flap of the greater pectoralis muscle in reconstructive cervicofacial surgery. Apropos of 27 flaps].

The authors review 27 pectoralis major myocutaneous flaps in head and neck cancer surgery. The indications and applications are discussed. Some technical aspects are pointed out. The results are analyzed and compared with data in the published literature. Because of its numerous advantages, the pectoralis major musculocutaneous flap does establish a real progress in the surgical treatment of head and neck cancer.

Adult↗
PubMed1983

The forearm fascia flap.

A new subcutaneous flap technic, derived from the chinese forearm flap has been demonstrated. It has been used to cover large cutaneous defects of the hand, especially when the extensor tendons were exposed. An excellent functional repair has been obtained in a single procedure avoiding large scar formation usually seen on the forearm after classical chinese fasciocutaneous flap.

Adult↗
PubMed1977

Studies on the possible influence of the so-called wound healing reaction on DNA synthesis in organ culture.

Tissue sectioning is a necessary preliminary step in the preparation of organ culture explants. The real extent of tissue damage in the "wound healing reaction" can be assessed by DNA isotopic labeling. The differential count of labeling indices between epithelial structures located at the margin of the explants and similar structures near the center was used to study the influence of tissue damage on DNA synthesis. Our results suggest a time-related influence of wound healing on labeling indices. This reaction has to be taken into account when DNA synthesis is used as an indicator of hormonedependency in vitro.

Autoradiography↗
PubMedDate not supplied

Skin microcirculation responses to severe local cooling.

When skin is exposed to cold, cutaneous blood flow is initially restricted due to sympathetic vasoconstriction. Prolonged exposure to cold has a secondary protective vasodilator effect. In the present study, the effects of severe and prolonged local cold on the cutaneous microcirculation were assessed. In 10 young healthy subjects, laser Doppler skin flux and flux motion were measured at the calf during 20 min of local ice cooling and 15 min subsequent recovery. In the 6th minute of cooling, mean skin flux decreased to 58 +/- 6% of the resting value (p < 0.05), then increased and reached 129 +/- 10% of the resting value at the end of the cooling period, followed by a phase of reactive hyperemia with a maximum of 225 +/- 24% (p < 0.05). Mean flux motion frequency, spontaneously present at rest with a frequency of 2.6 +/- 0.2 cycles/ min decreased rapidly during the first minutes of cold exposure, was absent during the 6th to the 10th minute, reappeared and started to increase from the 11th minute and reached 4.4 +/- 0.3 cycles/min during the recovery period (p < 0.05). This study seems to indicate that the phenomenon of protective increase of cutaneous microcirculatory blood flow consists of an initial phase of vasodilation, followed by a phase of active and enhanced microvessel vasomotor activity.

Adult↗