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Biomedical subjects

A De Moor

Publications and source records attributed to A De Moor.

At least 19 recordsLinked to original sources
PubMed2003

Optimisation of a vertical spray boom for greenhouse spraying applications.

The European Crop Protection Association (ECPA) and CLO-DVL joined forces in a project to stimulate a safe use of pesticides in Southern European countries. CLO-DVL optimised a method with mineral chelates to evaluate deposition tests. This quantitative method to evaluate spray deposits and to check spray distributions is used to assess two novel spraying techniques. Deposition tests with water-sensitive paper and mainly with the manganese and molybdenum chelates as tracer elements were performed with a manually pulled trolley and a motorised vehicle both equipped with vertical spray booms. Filter papers were attached to the tomato and pepper plants at several heights to obtain an indication of the spray distribution in the crop. Particular attention was paid to the effect on the spray distribution of the vertical nozzle distance (35 cm vs. 50 cm) and the spray distance to the crop. The tests proved that a nozzle spacing of 35 cm delivers a much better spray distribution than one of 50 cm. The optimal spray distance for flat fan nozzles with a spray angle of 80 degrees and a nozzle spacing of 35 cm is about 30 cm.

Aerosols↗
PubMed2001

Evaluation of excision, cryosurgery and local BCG vaccination for the treatment of equine sarcoids.

Ninety-five horses with sarcoids were subjected to three types of treatment: surgical excision (conventional or carbon dioxide laser), cryotherapy or local BCG vaccination. The type of treatment was selected on the basis of the size, location and clinical appearance of the tumours. The choice between conventional and laser excision was empirical. A successful outcome was obtained in 11 of 14 (79 per cent) of the horses treated by cryosurgery, 18 of 27 (67 per cent) treated by BCG vaccination, 18 of 22 (82 per cent) treated by conventional excision, and 20 of 28 (71 per cent) treated with a carbon dioxide laser. For both excision methods, rigorous measures were taken to avoid autoinoculation and to ensure a wide margin of normal skin. The probability of local recurrence after excision was significantly higher for large sarcoids and sarcoids which had previously failed to respond to treatment. In 10 of the 31 horses with remaining sarcoids, some or all of the untreated sarcoids were observed to regress spontaneously.

Animals↗
PubMed2001

PCR detection of bovine papilloma virus DNA in superficial swabs and scrapings from equine sarcoids.

The purpose of this study was to examine if bovine papilloma virus (BPV) DNA can be detected in superficial swabs or scrapings from equine sarcoids. Samples were obtained from 92 sarcoids and 20 non-sarcoidal control lesions. The polymerase chain reaction technique was used with a first primer set to check whether DNA extraction was successful, and with a second primer set specific for BPV-DNA. DNA isolation was successful in 88% of the swabs and 93% of the scrapings. All control lesions were negative for BPV-DNA.

Animals↗
PubMed2000

Partial tibial neurectomy in 113 Belgian blue calves with spastic paresis.

One hundred and thirteen double-muscled Belgian blue calves (69 males and 44 females) with spastic paresis (52 unilateral and 61 bilateral) were treated surgically by partial tibial neurectomy under caudal epidural anaesthesia. Telephone inquiries made at least three-and-a-half months later established that good results were obtained in 83.2 per cent of the calves; a considerable improvement was reported in 4.4 per cent which still had intermittent spastic contractions; severe hyperflexion of the hock necessitating early slaughtering was recorded in 4.4 per cent of the calves; and in 8 per cent there was little or no improvement.

Anesthesia, Epidural↗
PubMed2000

Proteus syndrome: MRI characteristics of plantar cerebriform hyperplasia.

Proteus syndrome is a rare congenital hamartomatous syndrome with a variety of abnormalities. It shares many features with other congenital hamartomatous disorders, but cerebriform hyperplasia of the soles and the palms is known as a quite distinctive characteristic in the dermatologic literature. The purpose of this case report is to demonstrate the MRI features of plantar cerebriform hyperplasia in a 9-year-old boy with known Proteus syndrome.

Child↗
PubMed2000

Histopathological characteristics of five clinical types of equine sarcoid.

The purpose of this study was to determine the characteristics of occult, verrucous, fibroblastic, nodular and mixed equine sarcoids. Ten tumours of each type were examined histologically and analysed for the presence of bovine papilloma virus (BPV)- DNA. All tumours were positive for BPV - DNA and showed an increased density of dermal fibroblasts. Epidermal hyperplasia, hyperkeratosis, rete peg and 'picket fence' formation were only found consistently in the verrucous and mixed types and were often not present in occult and nodular sarcoids. Immunohistochemical staining for Keratins 10 and 16, Ki67 and p53 showed no important differences between the clinical types. It can be concluded that the presence of BPV - DNA and the increased density of dermal fibroblasts were the only common characteristics for all sarcoids of the different clinical types. The presence of other microscopic alterations was variable but could not be used in the differentiation of the clinical types based on histology.

Animals↗
PubMed1998

Conservative and surgical treatment of tibial fractures in cattle.

Ninety-five cattle with tibial fractures, all but one with a unilateral fracture, were examined between 1990 and 1994. The feasibility of repairing the fracture was assessed radiographically, also taking into account the bodyweight and value of the animal. Twenty-two cattle were slaughtered. Conservative treatment with stall confinement and/or a splint or cast was applied in 18 cases, with satisfactory results in eight of them (44 per cent). They were fattened to normal bodyweight, but they all had a severe deformity of the affected leg. In 55 animals, the fractures were fixed externally with Steinmann pins and methylmethacrylate bridges under image-intensified fluoroscopy. Ten of them could not bear weight on the affected leg and were slaughtered before the pins were removed. In the remaining 45 animals the pins were removed after a mean (sd) period of 71 (14) days. Four animals re-fractured the affected leg shortly after the pins were removed and six others were slaughtered prematurely because of inadequate weight bearing. The results were successful in 35 cases (64 per cent). Slight deviations of the affected leg and/or the contralateral leg were often observed. The overall survival rate of the cattle with tibial fractures was 45 per cent.

Animals↗
PubMed1996

Surgical treatment of urethral dilatation in seven male cattle.

The surgical treatment of urethral dilatation in the perineal region of seven young Belgian blue bulls is described. Urethrostomy under local anaesthesia in the standing animal resulted in a successful outcome in three of them. The possible aetiological factors and consequences of this syndrome are discussed.

Animals↗
PubMed1995

Surgical aspects of intestinal atresia in 58 calves.

Fifty-eight calves with intestinal atresia at different sites were treated surgically. In only four of the animals the anal opening was reconstructed directly in the perineal region. In the remaining cases the final extent of the atresia was confirmed by a right flank laparotomy and in seven calves an anal opening was made in the perineal region and in seven calves the opening was made in the right flank. The remaining 40 calves were euthanased for different reasons. Seven of the 18 surgically corrected animals made a satisfactory recovery.

Animals↗
PubMed1993

Surgical treatment of urethral obstruction due to urolithiasis in male cattle: a review of 85 cases.

Eighty-five male cattle with urethral obstruction due to urolithiasis were treated by surgery. In most cases local anaesthetic techniques combined with sedation were applied to the dorsally recumbent animals. The penis was transected and transposed in animals with a ruptured urethra. A ruptured bladder was repaired by a paramedian abdominal approach. The bladder was fistulated through the ventral abdominal wall when no alternative treatment was possible. Complications related to the different surgical interventions are described. Only 35.3 per cent of the animals recovered satisfactorily.

Animals↗
PubMed1992

Laryngotomy as a treatment for chronic laryngeal obstruction in cattle: a review of 130 cases.

One hundred and thirty cattle with chronic laryngeal obstruction were treated by surgery; the diagnostic and operative techniques are discussed. A simplified technique using local anaesthesia of the laryngeal area was used in sedated calves weighing up to 200 kg. Inhalation anaesthesia through a distal tracheotomy was needed in heavier animals. Complications related to the surgical intervention are described. The animals were reviewed from five months to over one year after discharge from the clinic. The long term survival rate of the 130 animals was 58 per cent. The results after surgery were excellent in 40.9 per cent and good in 15.2 per cent of the animals.

Airway Obstruction↗
PubMed1992

Influence of hypertonic saline solution 7.2% on different hematological parameters in awake and anaesthetized ponies.

The influence of hypertonic NaCl 7.2% infusion (4 ml/kg of body weight [BWT]) on plasma (PV) and blood (BV) volumes, sodium (Na), chloride (Cl), potassium (K) plasma concentrations, osmolality (Osm), total protein content (TP), packed cell volume (PCV) and red blood cell count (RBC) was studied in five standing and anaesthetized ponies (standard halothane anaesthesia). Arterial blood gases were followed in the anaesthetized ponies. Isotonic NaCl 0.9% (4 ml/kg of BWT) was used as a placebo in the standing ponies. Isotonic solution in the standing ponies induced few changes: only small decreases in K, TP, PCV and RBC were observed. Na, Cl and Osm increased significantly after the NaCl 7.2% infusions in the standing and anesthetized ponies. Significant decreases in PCV, RBC and TP after the administration of hypertonic solutions were determined and were in both groups clear indications of an occurring hemodilution although no significant increase in PV and BV could be demonstrated. An increase in diuresis characterized by numerous micturitions was observed in the standing ponies and during the recovery period after anaesthesia. Apparently, the occurring fluid shift towards the intravascular compartment was partly compensated by an increase in diuresis. The decreases in PCV, RBC and TP were less severe in the anaesthetized ponies compared to the changes observed in the standing ponies. Stress responses during anaesthesia might explain this finding. K increased abnormally at the end of anaesthesia, probably due to minimal muscle damage induced by the dorsal recumbent position. Arterial blood gases did not change after the administration of NaCl 7.2% solution during anaesthesia. No specific clinical side-effects related to the use of hypertonic solution could be observed in the standing and anaesthetized ponies. Further studies are necessary to investigate the effects of hypertonic NaCl solution in horses with a disturbed fluid balance (hypovolemia).

Animals↗
PubMed1991

Influence of digoxin followed by dopamine on the cardiovascular depression during a standard halothane anaesthesia in dorsally recumbent, ventilated ponies.

The influence of digoxin (0.01 mg/kg) given as an intravenous bolus followed by dopamine at different infusion rates (1.25, 2.5 and 5.0 micrograms/kg/min) on the cardiovascular depression during a standard halothane anaesthesia was studied in dorsally recumbent ventilated ponies. Preanaesthetic digitalization induced no clear positive cardiovascular effects over 30 minutes, except for non-significant increases in mean pulmonary artery pressure and total pulmonary resistance. These changes were probably time-related. No specific side-effects related to the fast intravenous digitalization were noticed. Dopamine at lower infusion rates (1.25 and 2.5 micrograms/kg/min) given minimally 30 minutes after the digitalization did not induce further changes (only minor non-significant increases in cardiac output and systemic blood pressure). Dopamine infusions at a higher infusion rate (5.0 micrograms/kg/min) improved the cardiovascular depression (significant increases in cardiac output and systemic blood pressure while total peripheral resistance tended to decrease). Heart rate, blood gases and total pulmonary resistance remained constant. The combination of a fast acting inotropic agent, dopamine, and a slow acting inotropic drug, digoxin, induced positive effects in reversing the cardiovascular depression and might therefore be useful during clinical anaesthesia in the horse.

Anesthesia↗
PubMed1991

Cardiovascular effects of low dose calcium chloride infusions during halothane anaesthesia in dorsally recumbent ventilated ponies.

The effects of calcium chloride administered at low infusion rates on the cardiovascular depression and the blood calcium balance were studied during a constant halothane anaesthesia in dorsally recumbent ventilated ponies. A pronounced cardiopulmonary depression characterized by decreases of all cardiac parameters and lowering of the mean arterial blood pressure was observed after the initial anaesthetic stabilization period of 30 minutes in the ponies. A significant decrease in the total calcium plasma concentration together with a constant ionized and complexed calcium fraction was present after the stabilization period. Calcium chloride administration at different infusion rates (0.1, 0.2 and 0.3 mg/kg/min) induced a dose-dependent increase in mean systemic blood pressure, probably due to the observed increase in total peripheral resistance. A dose-dependent gradual decrease in heart rate, probably mediated by the increased vagal activity, was observed after the calcium infusions. The stroke volume increased also in a dose-dependent way. Cardiac output, arterial blood gases or packed cell volume were not influenced by the exogenous calcium infusions. The observed increases in mean pulmonary artery pressure and total pulmonary resistance were probably time-related responses. Overall, only the effects of the exogenous calcium on the peripheral vasculature, namely a vasoconstriction leading to an increase in blood pressure, were present in this study. Although LV dP/dt max was not measured in this study, minor positive inotropic effects of the exogenous calcium infusions might nevertheless be possible since the observed increase in stroke volume could be an indication of an increase in the ventricular contractility function. The different fractions of the calcium in the plasma (total and ionized & complexed calcium) increased during the exogenous calcium infusions but the proportion of the fractions remained always constant.(ABSTRACT TRUNCATED AT 250 WORDS)

Anesthesia, Inhalation↗
PubMed1991

Laminitis in the pony: conservative treatment vs dorsal hoof wall resection.

The clinical and radiographic findings in 21 ponies with laminitis and its treatment and results are described. All ponies received non-steroidal anti-inflammatory drugs. All were fed hay and no concentrates. They were box rested for varying periods depending on clinical improvement. Dorsal hoof wall resection was performed in 11 ponies and all regained complete soundness. To shorten the period of non-activity, working ponies were shod and the hoof wall defect was packed with technovit or a combination of glue with cotton cuttings. Ten were treated conservatively; two recovered completely, four remained lame and four were killed because of recurrent laminitis.

Animals↗
PubMed1990

Haemodynamic changes during sedation in ponies.

The cardiovascular changes induced by several sedatives were investigated in five ponies with a subcutaneously transposed carotid artery by means of cardiac output determinations (thermodilution technique), systemic and pulmonary artery pressure measurements (direct intravascular method) and arterial blood analysis (blood gases and packed cell volume). The cardiovascular depression (decrease in systemic blood pressure and cardiac output) was long lasting (greater than 90 min) after administration of propionylpromazine (0.08 mg/kg intravenous (i.v.)) together with promethazine (0.08 mg/kg i.v.). The phenothiazine-induced sedation was not optimal. alpha 2-Agonists (xylazine (0.60 mg/kg i.v.) and detomidine (20 micrograms/kg i.v.)) induced initial but transient cardiovascular effects with an increase in systemic blood pressure and a decrease in cardiac output for about 15 min. Second degree atrioventricular blocks and bradycardia were seen during this period. The cardiovascular depression was more pronounced during detomidine sedation. Atropine (0.01 mg/kg i.v.) induced a tachycardia with a decrease in stroke volume but did not alter the cardiac output or other cardiovascular parameters. It prevented the occurrence of the bradycardia and heart blocks normally induced by xylazine or detomidine. Atropine potentiated the initial hypertension induced by the alpha 2-agonistic sedatives (especially detomidine). The decrease in cardiac output induced by xylazine, and to a lesser extent by detomidine, was partially counteracted when atropine was given in advance. The atropine-xylazine combination seemed the best premedication protocol before general anaesthesia as it only resulted in minor and transient cardiovascular changes.

Animals↗
PubMed1990

A preliminary study on the effects of atropine sulphate on bradycardia and heart blocks during romifidine sedation in the horse.

Romifidine (STH 2130-Cl or Sedivet) is an alpha 2-agonistic imino-imidazol sedative for intravenous use in horses recently developed by Boehringer Ingelheim, Vetmedica GmbH. An exploratory study was done in nine warm-blood horses, randomly divided into three groups, which received different dosages of romifidine (0.04, 0.08 and 0.12 mg/kg of body weight (BWT) intravenously (i.v.)) with at least one week's interval between tests. Romifidine induced a marked bradycardia accompanied by second degree atrioventricular (AV) block and some sinus blocks at all tested dosages. A placebo (NaCl 0.9% i.v.) given 5 min before and after romifidine did not affect the cardiac disturbances induced by romifidine. A low dose of atropine sulphate (0.005 mg/kg of BWT i.v.) given 5 min before romifidine counteracted the bradycardia and caused a normal to increased heart rhythm at all romifidine dosages. A higher dose of atropine sulphate (0.01 mg/kg of BWT i.v.) administered 5 min before sedation induced a tachycardia (average 70 beats/min) at all romifidine dosages and completely prevented the bradycardia and the heart blocks. The positive chronotrope effects of atropine sulphate were attenuated by increasing doses of romifidine. The effects of atropine sulphate (low or high doses) given 5 min after romifidine only appeared after 5 min. Both dosages counteracted the bradycardia and suppressed the heart blocks. No atropine-dependent side effects were observed in non-fasted horses. The degree of the romifidine induced sedation was not affected by the use of atropine sulphate given before or after romifidine.

Adrenergic alpha-Agonists↗