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Biomedical subjects

A De Roode

Publications and source records attributed to A De Roode.

3 recordsLinked to original sources
PubMed1995

The effect of midazolam premedication on implicit memory activation during alfentanil-nitrous oxide anaesthesia.

Eighty-three patients were given midazolam 0.1 mg.kg-1 by intramuscular injection as premedication before general anaesthesia with alfentanil-nitrous oxide. During anaesthesia patients were presented (through headphones) with either statements about common facts of some years ago (group A) (n = 43) or new verbal associations, e.g. names of fictitious, nonfamous people (group B) (n = 40). In a previous study with the same anaesthetic technique, but without premedication there was significant activation of implicit memory (p < 0.001). In this study we found no explicit or implicit memory for the auditory information presented during anaesthesia. Midazolam premedication can prevent implicit memory activation during alfentanil-nitrous oxide anaesthesia.

Adult↗
PubMed1992

Unconscious learning during anaesthesia.

Forty-three surgical patients were, during general anaesthesia, presented (via headphones) with either statements about common facts of some years ago (group A), or new verbal associations, i.e. the names of fictitious, nonfamous people (group B). None had any recall of intra-operative events. In a postoperative test of indirect memory, patients in group A answered more questions about the 'common facts' correctly than those in group B (p < 0.005), which reflects the activation of pre-existing knowledge. Furthermore, patients in group B designated more 'nonfamous names' as famous (thus falsely attributing fame) than patients in group A (p < 0.001), which demonstrates that information-processing during anaesthesia can also take place as unconscious learning.

Adolescent↗