Mycophenolate mofetil monotherapy in stable liver transplant recipients with progressive renal failure.
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Adult↗
Biomedical subjects
A De Roover
Publications and source records attributed to A De Roover.
[Image of the month. Compensatory liver growth following right liver lobe transplantation in a liver donor and adult recipient].
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Female↗
[Update on pancreatic transplantation].
Pancreas transplantation significantly improves the quality of life as well as the survival of the diabetic patient. It is also associated with stabilization and reversal of secondary diabetic complications. Improvements in organ preservation, surgical techniques and immunosuppression have achieved one-year graft survival of more than 90% for combined kidney-pancreas transplant and 80% for isolated pancreas transplantation. Recipient evaluation must weigh the benefits of the procedure with the risk associated with surgery and chronic immunosuppression. Combined kidney-pancreas transplantation appears today as the best treatment for the diabetic patient with end stage renal disease. Isolated pancreas transplantation is reserved to non-uremic patients with severe diabetic complications or with brittle glycaemic control and severe impairment of quality of life.
Humans↗
[Alpha-1-antitrypsin deficiency. An indication for pediatric liver transplantation].
Alpha-1-antitrypsin deficiency is the most common inborn error of metabolism leading to liver transplantation, and the second cause of liver transplantation in children after biliary atresia. The authors report the case of a 6-year-old girl, who was suffering from end-stage liver disease secondary to alpha-1-antitrypsin deficiency. She was successfully treated by whole liver transplantation, the hepatic graft coming from a 3-year-old donor. Three months later she went back to school. The authors discuss the pathogenesis and the natural history of this frequent cause of liver transplantation in children.
Child↗
Laparoscopic live donor nephrectomy: initial experience.
Transplanting a kidney graft harvested from a live donor has been proposed and used to shorten the waiting time of kidney transplant candidates and to increase the graft pool. Live donor renal transplants have demonstrated better results in term of graft survival rates, compared to renal transplants harvested from brain dead donor. Recently, laparoscopic live donor nephrectomy has been introduced to reduce the live procurement morbidity. This lower morbidity may result in increased acceptance of the donor operation. We initiated a program of laparoscopic live donor nephrectomy in January 1997 and up until June 1998, three cases were successfully performed in our department. The purpose of this paper was to report the first case of this program and its first year of follow-up.
Adolescent↗
[Morphometric study of the lumbosacral plexus innervating the muscles of the rat pelvic floor].
Motoneurons of the pelvic muscles in the lumbo-sacral segment of the spinal cord have been extensively studied in different species. However, few informations occur in the literature about the individual morphology of each group of neurons and their connections. Thus, in the Rat we have studied the neuronal mapping of 5 pelvic muscles, bulbospongiosus, ischio-cavernosus, levator ani, sphincter ani, sphincter urethrae, using a retrograde tracer, the horseradish peroxidase (H.R.P.). Most of the muscles injected by H.R.P. receive their innervation from the motoneurons located in the homolateral side of the spinal cord. The motoneurons of sphincter ani (+/- 40) and those of the bulbo-spongiosus (+/- 50) have the same morphology. Their dendrites contact contralateral motoneurons. They are situated in the dorso-medial nucleus of the L5-L6 segments of the spinal cord. The motoneurons of the ischio-cavernosus (+/- 80) and those of sphincter urethrae (+/- 40) are situated in the dorsolateral nucleus of the L5-S1 segments of the spinal cord where they form two distinct groups. On the contrary, in the ventro-medial nucleus, the neurons are mixed. The dendrites in the dorso-lateral nucleus form an important longitudinal network. The motoneurons of the levator ani (+/- 50) are situated in the ventral nucleus of the L5-S1 segments. Our works demonstrate the significance of the dendritic networks: they could play a role in the synchronization and the activity of the pelvic muscles.(ABSTRACT TRUNCATED AT 250 WORDS)
Animals↗