Biomedical subjects
Publications and source records attributed to A De Toffoli.
The authors consider differences in answer of the first generation cephalosporins against several strains of Gram-negative and Gram-positive bacteria, and suggest a revision of the "class" concept as regards sensitivity response of the above mentioned cephalosporins.
Activities of four new Cephalosporins (Cephamandole, Cefoxitin, Cefuroxime, Cefotaxime) and of some of the most used Aminoglycosidic antibiotics were tested against Gram-negative bacteria (Pseudomonas and some Enterobacteriaceae) that are often formed to be multi-resistant. 266 strains were observed. An evident increase or resistance to Aminoglycosidic antibiotics was confirmed, while the new Cephalosporins demonstrated an remarkable activity against the majority of resistant bacteria, often superior to Aminoglycosidics.
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