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Biomedical subjects

A Debbagh

Publications and source records attributed to A Debbagh.

16 recordsLinked to original sources

[Primary adenocarcinoma of the bladder: report of a case].

The authors a case of primary adenocarcinoma of the bladder and studied the clinical, histological, therapeutical and evolutive aspects of this unusual tumor. It is a rare neoplasm that occurs for less than 2% of all bladder tumors and it is more prevalent in males between 50 and 60 years. The symptoms, exepting mucusuria, are non-specific, and hematuria is by far the most frequent presenting symptom. Different etiologies have been theorized, but this tumor is generally thought to arise through transitional epithelial metaplasia. The diagnosis is based on the pathologic anatomy examination. The treatment still not codified, but all of the authors advocate early aggressive surgery. The prognosis is poor.

Adenocarcinoma↗

[Bolande tumor in adults: apropos of a case].

Bolande's tumour or congenital mesoblastic nephroma is essentially a tumour of infants under the age of one year and is rare in adults, in whom only 10 cases have been described. The authors report the 11th case in a 30-year-old woman, in whom a right renal tumour was discovered during ultrasonography at 34 weeks of pregnancy. Radical nephrectomy was performed after delivery, with a favourable course at 3 years, with no recurrence or metastasis. The aetiopathogenic and diagnostic aspects are discussed, with emphasis on the possibility of a hormonal inducing factor in the histogenesis of this tumour.

Adult↗

[Spontaneous hematoma of the kidney. Apropos of 3 cases].

The objective of this study was to illustrate the diagnostic and therapeutic aspects of renal haematomas based on 3 cases observed in the Casablanca urology department and a review of the literature. In 50% of cases, the haematoma is secondary to adenocarcinoma or angiomyolipoma, requiring specific treatment.

Adenocarcinoma↗

[Retroperitoneal ganglioneuroma. Apropos of a case].

Ganglioneuroma is a rare tumour in adults. We report the case of a 26-year-old woman admitted in our department with right renal colic. Ultrasonography and computed tomography showed a heterogeneous retroperitoneal mass measuring 8 x 7 cm in diameter and displacing the ureteropelvic junction and right kidney anteriorly and laterally. The preoperative diagnosis was retroperitoneal tumour. Surgical exploration revealed a totally resectable retroperitoneal tumour with a histological diagnosis of ganglioneuroma.

Adult↗

[Appendiceal mucocele disclosed by a psoas tumor. Apropos of a case].

Mucocele of the appendix is a rare lesion. Rupture of appendicular mucocele into the psoas is uncommon. We report a case of a 77-year-old man, with psoas tumor on abdominopelvic ultrasonography and computed tomography. The preoperative diagnosis was type III hydatid cyst of the psoas, psoas tumor or retroperitoneal mass. Surgical exploration revealed an appendicular mucocele ruptured into the psoas. Appendicectomy was performed with an uneventful postoperative course after 3 years. The authors discuss the diagnostic and therapeutic problems raised by this rare lesion.

Aged↗

[Primary urothelial carcinoma of the urethra. Apropos of a case].

We report an unusual case of primary transitional cell carcinoma in the bulbar urethra. The patient was a 52-year-old man with a history of sexually transmitted disease. The clinical presentation was bladder retention with urethral bleeding. Radiological examination and cystoscopy showed a bulbar urethral tumor. The pathological diagnosis was Grade III transitional cell carcinoma with invasion of the corpus spongiosum (T2). Partial resection of the urethra was performed and the patient has been without evidence of disease for two years.

Carcinoma, Transitional Cell↗

[Tumors of the bladder in women. Epidemiologic and therapeutic aspects. Apropos of 40 cases].

Bladder tumours in women. Epidemiological aspects and treatments, based on a series of 48 cases. Bladder tumours are more frequent in men than in women, in whom they present certain epidemiological, clinical and therapeutic characteristics. The authors report a retrospective study of 48 cases of bladder tumour in women, observed in the urology department over a 20-year period. These tumours represented 4.2% of all bladder tumours. The patients had a mean age of 59 years (range: 29 to 77). Only one patient was a smoker (2%). Haematuria was present in 93% of cases, and signs of bladder irritation were present in 60% of cases. All tumours were transitional cell carcinomas. The tumour was classified as stage 0 in 10 cases (20.9%), stage A in 15 patients (31.2%), stage B in 22 patients (45.8%) and stage C in 1 case (2.1%); no patients (0%) were classified as stage D. Our therapeutic protocol was established as a function of the stage of tumour invasion. For example, superficial tumours were treated conservatively by transurethral resection, either alone or combined with intravesical instillation. Radical surgery was performed whenever possible for invasive tumours. External urinary diversion was performed in 11 cases, ureterosigmoidostomy in 3 cases and enterocystoplasty in 5 cases. The clinical course of the 15 superficial tumours was marked by recurrence in 5 cases, while that of the 23 invasive tumours was marked by local recurrence (3 cases), renal failure (1 case) and 3 deaths.

Administration, Intravesical↗

[Traumatic rupture of the corpus cavernosum].

Traumatic rupture of the corpus cavernosum is relatively frequent in the authors' experience. Based on the study of a series of 80 cases and a review of the literature, the authors analyse the diagnostic and therapeutic aspects and outcome of this disease. The patients in this series had a mean age of 30 years. Meticulous and intimate clinical interview demonstrated that the commonest mechanism is forced manipulation of the erect penis (68%). Clinical examination localized the site of the fracture (proximal: 57%, distal 43%). The fracture was unilateral (78 cases), rarely bilateral (2 cases) and associated with complete rupture of the urethra (1 case). Treatment was surgical in 79 patients. A distal semicircumferential incision was used in the case of bilateral rupture, distal rupture and associated urethral lesion (34 cases). A favourable course was observed in 86% of cases. However, 9 postoperative complications (12.5%) were observed (6 cases of fibrous plaques, 3 cases of chordee of the penis), due either to the extent of the haematoma or to the delay in treatment. Traumatic rupture of the corpus cavernosum is a disease of young adults, which requires early surgical treatment with an approach adapted to the type of lesions.

Adolescent↗

[Epidermoid carcinoma of the bladder. Apropos of 14 cases].

The authors report 14 cases of squamous cell carcinoma of bladder over a period of 20 years. All patients were male, with a mean age of 56 years. A history of urogenital bilharziasis was reported in 2 patients and 10 patients were smokers. Hematuric cystitis was the commonest presenting feature and infiltration of the bladder base was detected on rectal palpation in 10 patients. The patients consulted late in the course, at the stage of upper urinary tract repercussions (11 cases) and computerized tomography showed locoregional extension in 5 cases. 12 total cystoprostatectomies were performed and 2 patients were treated exclusively by radiotherapy. The long-term course was marked by urethral recurrence in 3 patients. The etiopathogenesis, diagnosis, treatment and clinical course of these tumors, which are often aggressive, are reviewed.

Aged↗

[Primary pyogenic abscess of the psoas muscle. Apropos of 5 cases].

The authors discuss the diagnostic and therapeutic aspects of primary pyogenic abscess of the psoas muscle based on a series of 5 cases. Five patients between the ages of 15 and 64 years (mean: 38.2 years) were admitted to the urology department between January 1994 and December 1996 with fever, abdominal pain and low back pain, and psoitis in 1 case. The mean delay to consultation was 42 days. Clinical examination revealed a painful mass in the lumbar region and flank in 5 cases. Leukocytosis was detected in 5 patients. Radiological examination demonstrated loss of the lateral border of the psoas in 4 cases. Ultrasonography showed an enlarged psoas muscle in every case with a hypoechoic mass in 2 cases and a heterogeneous mass in the other 3 cases. Computed tomography, performed in 2 patients, confirmed the ultrasound findings in 1 case and excluded the diagnosis of type IV hydatid cyst of the psoas muscle in the other patient. The abscess was evacuated by percutaneous drain in 1 patient requiring a second percutaneous drainage for reconstitution of the abscess. Surgical drainage was performed immediately in 3 patients and after failure of antibiotic treatment in 1 patient. The hospital stay did not exceed 7 days after surgical drainage, but was 25 days after the first percutaneous drainage and 20 days after the second percutaneous drainage. The authors emphasize the multiple advantages and efficacy of surgical drainage of psoas abscess.

Abdominal Pain↗

[Retroperitoneal liposarcoma. Two cases].

Concerning two cases of liposarcomas developing in the retroperitoneal space, the characteristics of these rare tumors are reviewed. They are the most frequent mesenchymal tumors. Often, they are uncovered by palpable abdominal mass or when they compress adjoining organs. Computed tomography has proved valuable in the diagnosis of these lesions. Surgical removal is the treatment of choice. Recurrences are frequent and prognosis is poor.

Adult↗

[Obstructive anuria. Thirty cases].

The authors report 30 cases of obstructive anuria during the last fifteen years. The anuria was secondary to lithiasis in 60 per cent, in 26.6 per cent to pelvic cancer and in 13.4 per cent to retroperitoneal fibrosis. The diagnosis was facilitated by ultrasonography. Emergency treatment of obstructive anuria is based on urinary diversion by ureteral stent or by percutaneous nephrostomy under ultrasound control. Later the treatment depend of etiology.

Adult↗

[Urogenital tuberculosis. Diagnostic aspects].

Urogenital tuberculosis still represents a major urologic problem in the northern part of Africa, and it is a serious disease because its diagnosis is usually late. Furthermore, the affection is frequently bilateral, which may cause the renal failure. 86 cases of urogenital tuberculosis have been reviewed. Our patients were young adults (average age: 34 year old). Cystitis is the most frequent sign (74%), hematuria, lumbar pain, genital signs and nephrologic signs are not rare. Urine was negative in 46 patients, and amicrobial leucocyturia was present in 24 cases. Diagnosis relies on a range of signs, especially intravenous pyelography that has an important place. Endoscopic biopsy did confirm the diagnosis of tuberculosis in 12 patients. Generally, definitive diagnosis was based on the histologic study of the operative specimen.

Adolescent↗

[Bilateral fracture of the corpus cavernosum with complete rupture of the urethra].

About a case of complete rupture of the urethra associated to bilateral fracture of the corpus cavernosa following manipulation of the penis in erection, we stress the interest of an early surgical treatment, which permits a precise lesional diagnosis and an immediate reparation of the lesions. It is even the best warrant of a correct functional recovery.

Adult↗