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Biomedical subjects

A Del Cañizo Alvarez

Publications and source records attributed to A Del Cañizo Alvarez.

8 recordsLinked to original sources

[Goldenhar syndrome: a polymalformation syndrome with conductive hearing loss].

We report the case of a 9-years-old girl showing at examination facial asymmetry, right ear with II degree dysplasy and degree III in the left ear (according Marx classification), cleft palate, renal agenesy, scoliosis and hypoplasy of the left thumb. Otoscopically both external ear canals looked very narrow and very upright positioned. The drumhead image recalling that of chronic mucoid effusion. The measurement of hearing through pure-tone audiometry, PEATC, and tympanometry resulted in a pattern of bilateral transmissive pantonal hearing impairment accounting for 50-60 dB. Scoliosis was due either to bars or hemivertebrae or even to an atlas occipitalization. Chromosoma caryotype was normal.

Abnormalities, Multiple↗

[Study of Cyfra 21-1 as a new tumor marker for the diagnosis of epidermoid carcinoma of the head and neck].

Serum concentrations of Cyfra 21-1, a soluble cytokeratin fragment, were evaluated in 157 healthy patients, 66 patients with benign ear, nose or throat disease, and 102 patients with untreated epidermoid carcinoma of the head and neck. The technique had a sensitivity of 53.9% and specificity of 98.4% for a cutoff value of 1.5 ng/ml. Cyfra 21-1 levels differed significantly with tumor location (p < 0. 005) and tumor stage (p < 0.005), but not with the degree of histological differentiation.

Antigens, Neoplasm↗

[Treatment of chronic snoring with CO2 laser].

Laser-assisted uvulopalatoplasty (LAUP) is an effective surgical procedure for treating habitual snoring. It is performed under local anesthesia as an outpatient procedure and consists of enlarging the oropharyngeal air space and restructuring the uvula, velum, and pharyngeal pillars. We used LAUP in 112 patients with upper airway resistance syndrome (UARS) (Lipman grade II) over the last three years and achieve a care rate of 87.5%.

Adult↗

[Changes in the nuclear morphometry in oropharyngeal epidermoid carcinoma after induction chemotherapy].

A cytomorphic, stereological study was made by computerized image analysis of six nuclear morphometric variables and one stereological nuclear variable. Variables were measured on 150 randomly selected tumor cells in oropharyngeal biopsies from 44 patients with oropharyngeal cancer who had not responded completely to induction chemotherapy. The nuclei of tumoral cells were larger (mean nuclear area, perimeter, and volume), more rounded, and had a less irregular nuclear contour index.

Adult↗

[Benign necrotizing osteitis of the external ear canal. A report of a clinical case].

Benign necrotizing osteitis of the external ear canal is a process of unknown origin. This necrotic process with sequestration of the tympanic bone occurs in healthy, non-diabetic patients. It should be differentiated from malignant otitis externa and radionecrosis of the tympanic bone. A case is reported and the literature on this rare clinical entity is discussed.

Aged↗

[Nasal leiomyosarcoma].

Leiomyosarcoma is an infrequent soft-tissue tumor that generally occurs in the myometrium and gastrointestinal tract. Primary tumors of the veins are unusual and generally occur in the inferior vena cava and only exceptionally in peripheral veins, such as the jugular or its branches. We report a case of leiomyosarcoma located in the left inferior turbinate. The 87 year-old male patient presented nasal obstruction and recurrent nosebleed. He had pulmonary and mediastinal metastases at the time of diagnosis.

Aged↗