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Biomedical subjects

A Del Gaudio

Publications and source records attributed to A Del Gaudio.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Adrenal cysts].

Suprarenal cysts may be clinically silent and discovered by chance, or they may present clinically if they attain marked dimensions by means of compression of surrounding formations. Examinations that lead to precise diagnosis are: direct abdominal X-ray integrated with scanning, echoscanning, urography and selective arterial and especially venous vasography. Two clinical cases that may be considered typical of the two varieties, true cyst and pseudo-cyst, are reported.

Adrenal Gland Diseases↗
PubMedDate not supplied

The tuberous breast syndrome.

The tuberous breast syndrome is the result of a complex series of defects with various degrees of expression. However, much confusion has been generated in the literature by the use of often inadequate terminology, which is partly the cause of multiplicity of managements being proposed that mainly aim to correct the major defect and not the entire syndrome. The surgical approach adopted by our group stems from the improvement of classic techniques, consisting essentially of a combination of periareolar mastopexis, additive mastoplasty, and gland base enlargement by cross incision. Our results were fully satisfying both aesthetically and functionally. We achieved a correct shape, resolved ptosys and reduced areolas with no double-fold effect, and attained good symmetry in more complex unilateral cases.

Adult↗
PubMedDate not supplied

The impact of genetics on Crohn's disease.

BACKGROUND/AIMS: Reports focusing on the familiarity and "pedigree" of patients with Crohn's Disease (CD) are increasing. The study of the role of genetics as a predisposing factor in providing the ideal milieu upon which environmental agents and immuno-inflammatory responses may act, could be paramount in finding the pith of the etiopathogenesis of this disease. METHODOLOGY: In order to determine the impact of familiarity on CD, a series of 187 patients, managed between January 1965 and January 1997, was subdivided into two groups. In group I (145 pts.), the family history relied only on direct information from the patient, while in group II (42 pts.) a prospective study was carried out involving both close and distant relatives who were interviewed and, in some cases, clinically investigated. RESULTS: In this study, relatives with suspected CD were 9 out of 122 in group I patients (7.4%), while in the more detailed assessment of group II, 18 out of 42 cases (43%) had an ascertained CD familiarity. CONCLUSIONS: The importance of familiarity in the pathogenesis of CD may be higher than expected if properly sought for. Reports on the possibility that the onset of CD may be strongly influenced by genetics, favor our hypothesis that the true etiology may find its base in a hemolymphatic disorder of the mesentery followed by superimposed inflammatory responses.

Adolescent↗
PubMedDate not supplied

Interposition of the first jejunal loop for reconstruction after total gastrectomy.

A new technique of reconstruction after total gastrectomy by interposing the first jejunal loop between the esophagus and the duodenum, is described. Vascular and neural integrity of the interposed intestinal segment is "guaranteed", resulting in acceptable muscular activity on intestinal contents and partial digestive function, with limited post-operative complications. The interposed jejunal loop assumes reservoir function and permits almost normal eating habits. Application of this technique to 18 patients undergoing total gastrectomy has resulted in a more than satisfactory post-operative functional and nutritional status over a one to 14 year follow-up period.

Aged↗
PubMedDate not supplied

Ectopic ACTH syndrome.

The recognition of extrapituitary ACTH-secreting tumors is of great importance, not only theoretically but also in practice, in that it permits rational and radical therapy of the relative Cushing's syndrome and avoids more traumatic and risky surgery such as the destruction of the hypophysis and total adrenalectomy. In some cases, however, a systematic search for these tumors, which can be extremely small, is unsuccessful even when the most modern diagnostic tools are employed. Thus, it is still sometimes necessary to resort to total adrenalectomy for provisional control of the Cushing's syndrome, delaying definitive treatment until the tumor makes itself evident. Two clinical cases are described in which, although elements suggesting the possibility of an ectopic neoplasia were present at the time of adrenalectomy, they were not recognized as such, and the tumor responsible for the syndrome was not identified until many years later.

ACTH Syndrome, Ectopic↗
PubMedDate not supplied

Pheochromocytoma and renal artery stenosis.

Cases with concurrent pheochromocytoma and renal artery stenosis, two "surgically curable" hypertensive disorders, are rare. The stenosis is generally secondary to direct compression or stretching of the renal artery by the tumor. Five such cases are reported. Sometimes the tumor and the renal artery stenosis occur independently giving rise to some pathogenetic queries. Diagnosis and therapy are briefly discussed.

Adrenal Gland Neoplasms↗