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Biomedical subjects

A Del Prete

Publications and source records attributed to A Del Prete.

32 records · Page 2Linked to original sources
PubMed1982

The AC/A ratio and convergence in hypermetropia corrected with spectacles or contact lenses.

Some hypermetropes, when corrected with contact lenses, appear to have a much smaller AC/A ratio than when corrected with spectacle lenses. Ocular convergence measured with contact lenses is greater than that measured with spectacles. Studies were carried out to establish the cause of these effects. Theoretical considerations are compared with the experimental results obtained. This study emphasizes the importance of the different amounts of magnification induced by contact lenses as compared with spectacles.

Adolescent↗
PubMed1979

Genetic study and surgical correction of euryblepharon.

Euryblepharon is a rare congenital anomaly of the palpebral fissure which consists of an increase in its width. A case has been described in which this characteristic is very marked, and associated with ectropion, lagophthalmos, corneal ulcers; also congenital malformations as twisted feet, hypospadia and inguinal hernia. Apart from a limited increase of the palpebral fissure in the mother, the familiar anamnesis is negative, and likewise examination of the cariogram and research of eventual metabolic modifications. An estimation of the various surgical techniques proposed revealed insufficient strictness regarding the standards generally followed in palpebral plastic surgery. Consequently, a technical variation was set up that will satisfy the needs of correct anatomical-surgical practice.

Abnormalities, Multiple↗
PubMedDate not supplied

Topically applied levobunolol does not cause changes in the corneal endothelium.

The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. The untreated fellow eye served as a control. The number of endothelial cells, determined with a McIntyre eyepiece and an Eisner's contact lens, was not affected by levobunolol therapy. In addition, the morphology of the cell did not appear to be affected by the drug.

Administration, Topical↗
PubMedDate not supplied

Long-term effects of befunolol on the corneal endothelium and the consensual ophthalmotonic reaction.

In a double-blind study, 30 patients with ocular hypertension were randomly assigned to receive one drop of 0.5% befunolol or placebo (the drug vehicle) in each eye twice daily for 120 days. The befunolol used contained no preservatives. Before and after treatment the number and shape of the endothelial cells of the five corneal sectors were evaluated. After 120 days of twice-daily application of befunolol or placebo, no changes in the shape or density of the corneal cells were found in any patient. No differences in the patients receiving befunolol or placebo were noted. The consensual ophthalmotonic reaction was studied in 15 of the patients before and after befunolol administration. A significant decrease in intraocular pressure was noted at 30 minutes and at 1, 2, 3, 4, 5, and 6 hours after befunolol. Intraocular pressure also decreased significantly at 1 to 4 hours after placebo, and then returned to pretreatment levels at 6 hours.

Adrenergic beta-Antagonists↗
PubMedDate not supplied

[Monitoring of body temperature during fiber optics phototherapy].

Fiberoptic phototherapy is a new technique for treatment of neonatal hyperbilirubinemia; in comparison with conventional phototherapy this new technique shouldn't increase body temperature during treatment. We have recorded body temperature of 13 term newborns with hyperbilirubinemia during 18 periods of treatment and compared the records with physiologic body temperature in the same babies. No increase over normal value during treatment nor significative difference during and after treatment has been observed.

Body Temperature↗
PubMedDate not supplied

[Therapy of neonatal infection caused by group B beta-hemolytic Streptococcus].

Expectant therapy for early Group B Streptococcus onset septicemia must provide coverage against other microorganism, such as L. Monocytogenes, H. Influenzae and S. Pneumoniae. It is possible to administer a combination of antimicrobial agents with activity against all or the most likely pathogens. Thus initial expectant therapy includes a broad spectrum semisynthetic penicillin (e.g. ampicillin) and an aminoglycoside (e.g. netilmicin). Vancomicin, teicoplanin and cefotaxime may also be used. Supportive therapy consists on temperature control, i.v. administration of fluids, acid-base balance and electrolytes monitoring, seizures control and ventilation. IV immunoglobulins, granulocyte and serum transfusion are also used. The G-Colony Stimulating Factor (G-CSF, filgastrim) usage is also reported.

Age Factors↗
PubMedDate not supplied

Evaluation of corneal thickness and endothelial cells before and after excimer laser photorefractive keratectomy.

BACKGROUND: The possible endothelial damage induced by photorefractive keratectomy was investigated in myopic eyes. METHODS: A morphometric analysis of the endothelial cells was performed in 19 patients before and 2 months after photorefractive keratectomy for the correction of various degrees of myopia. Central ultrasonic pachometry was also recorded at the same examination times. RESULTS: No significant changes (p = .816) of the endothelial cell density were found between preoperative and postoperative measurements. The pleomorphic index did not show any significant changes after treatment (p = .955). Central corneal thickness was reduced to a various extent (range from 50 microns to 250 microns) according to the amount of myopic correction intended. CONCLUSIONS: Our preliminary data suggest that photorefractive keratectomy for the correction of myopia does not induce endothelial cell damage, at least in the short term.

Adolescent↗