PubMed Health⌕ Search

Biomedical subjects

A Dessypris

Publications and source records attributed to A Dessypris.

14 recordsLinked to original sources
PubMed1977

Marathon run I: effects on blood coagulation and fibrinolysis.

Blood coagulation and fibrinolysis were assessed in 13 Finnish amateur runners aged 31 to 48, and one 65-year old taking part in a non-competitive marathon (42.2 km). After the run the mean values of partial thromboplastin time showed a very significant shortening, whereas the mean values of the prothrombin time and of plasma fibrinogen were not significantly altered. The mean values of euglobulin lysis time were significantly shorter and the mean values of fibrin degradation products increased highly significantly. After the run, protamine sulphate was positive or strongly positive in all subjects, whereas the ethanol gelation test was negative in all runners; no cryofibrinogen was detected in any participant. Thus, running a marathon race affects the haemostatic balance and activates the fibrinolytic mechanism. The effects of training and physical fitness on the above parameters are discussed.

Adult↗
PubMed1977

Marathon run II: Effects on platelet aggregation.

Platelet count and aggregation were assessed in 9 Finnish amateur runners aged 34 to 48, and one 65-year old taking part in a non-competitive marathon race (42.2 km). After the run the mean value of platelet count showed a very significant rise (p less than 0.001). The platelets were markedly more sensitive to both ADP and collagen-induced aggregation. A highly significant increase (p less than 0.001) was noted for both the intensity and velocity of platelet aggregation. The finding of platelet by hyperaggregability after prolonged strenous exercise even in trained subjects is discussed. It is concluded that a through medical examination of the haemostatic balance is recommended before a marathon race.

Adenosine Diphosphate↗
PubMedDate not supplied

[The super-marathon run (Spartathlon, 248 km): variations in blood gastrin].

Serum gastrin levels were determined in 21 male runners aged 21-57 years old before and after an ultra marathon (Spartathlon, Athens-Sparta, 248 km). 13 participants (group B) arrived to Sparta after a continuous run of 24-35 hours, while 8 stopped after 95-151 km (group A). The stress associated with such a strenuous run has resulted a 35% decrease of gastrin in group A and a 46% rise in group B. Gastrin levels (post-race) of group B were 56% lower than those of group A. The regulatory mechanisms of serum gastrin levels and the physiological adaptations related to such an exhaustive exercise are discussed.

Adult↗