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Biomedical subjects

A Dinu

Publications and source records attributed to A Dinu.

18 recordsLinked to original sources

The polar behavior of frog photoreceptors.

It was observed that the outer segments of the frog visual rods orient along the direction of an externally applied static electric field. The orientation ability of the rod outer segments seems to be fuelled by the cell energy. The dipolar moment per rod was determined using a model which considers rod outer segments as rigid dipoles interacting with the electric field in a viscous medium. The mean dipolar charge of ROS was determined as being (2.10 +/- 0.17).10(-14)C.

Animals↗

On the electrical conductivity of rhodopsin solutions.

Measurements were made on the conductivity of digitonin extracts of frog rhodopsin with and without previous light exposure. The light-dark difference in conductivity is observed at low concentrations of rhodopsin and detergent.

Animals↗

Studies concerning ATP dynamics in essential hypertension.

The use of Beckmann LS-7000 liquid scintillation spectrometer enabled us to develop a rapid and reproducible technique for the enzymatic microdosage of ATP by means of the bioluminescence reaction of the luciferin-luciferase system from the firefly. Changes of ATP concentration in the plasma, erythrocytes and cerebrospinal fluid of the hypertensive subjects as compared to the control ones have been revealed by means of this method. According to our results ATP concentration significantly increases in the plasma and cerebrospinal fluid and slightly modifies in the erythrocytes of the hypertensive as compared with control subjects. Correlation of data concerning the variation of ATP distribution in the different compartments (plasma, erythrocytes, cerebrospinal fluid) with those related to Na and K content in hypertensive and control subjects seems to be useful for some remarks on the molecular mechanisms in the essential hypertension.

Adenosine Triphosphate↗

Theoretical and experimental aspects of the possible role of calcium in some physiological and physiopathological phenomena.

The role played by calcium in some physiological and physiopathological phenomena is examined in the light of the intervention of calmodulin as a calcium regulatory protein. Data are presented concerning the interaction of some heavy metal ions with the erythrocyte membrane with special references to the modifications of calcium dynamics by Pb2. The results are discussed considering the interaction of heavy metal ions with the proteins of erythrocyte cytoskeleton and the role played by calmodulin in this interaction.

Blood Coagulation↗