[Pott's disease in an adult at the Dakar Hospital].
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Antitubercular Agents↗
Biomedical subjects
A Diop
Publications and source records attributed to A Diop.
[Contribution of the study of evolution of major electrolytes contents in the aqueous humour by X-ray fluorescence and ICP/AES].
INTRODUCTION: In the scope of this study, we had to do a qualitative and quantitative research of the current electrolytes as part of aqueous humour samples taken from patients suffering from cataract. MATERIALS AND METHOD: The tests were carried out by X-ray fluorescence and ICP/AES. The detection limit for the electrolytes varied from 0.005 to 0.1 ppm. RESULTS: The test results show iron (minimum 0.82ppm; maximum 25.50ppm), copper (0.28ppm; 8.17ppm), brome (5.18 ppm ; 55.82ppm), zinc (0.70ppm ; 9.78ppm ), sodium (1274.83ppm, 5211.67 ppm), potassium (55.52ppm ; 255.02ppm), calcium (26.46 ppm ; 256.81ppm), magnesium (5.77ppm; 70.33ppm). CONCLUSION: The data study have enabled us to establish reference value for each electrolyte. Study of the comparative reference values, together with the contents found in the normal aqueous humour, the normal and pathologic crystalline lens, has shown a noticeably low concentration of electrolytes and breakdown of the sodium/potassium pump which ensures ionic exchange between aqueous humour and the crystalline lens.
Adult↗
[Malaria morbidity in Barkedji, village of Ferlo, in Senegal Sahelian area].
A study of malaria morbidity was carried out from November 1994 to October 1995, in a Ferlo village (Barkedji) characterized by a long persistence of the temporary ponds. The objective was to evaluate the repercussions of the strong and long anopheles transmission in humans. A clinical follow-up of a group of residents was conducted at home every 10 days by an investigator trained for taking axillary temperature and making thick smears, when suspecting malaria. Were included in the group, 123 voluntary subjects among whom 50% were children under 10 years old. Any feverish subject (T degree >37 degrees 5) or subject presenting other malaria symptoms (headaches, hot body shivers, sweats, aches...) was regarded as having a malaria attack as well as a parasitemia >2500 P/mm3 in children aged of 0 to 14 years old and 1000 P/mm3 in the oldest. During the study subjects with at least one feverish access, plasmodium infection and malaria attack were 58%, 33% and 22%, respectively. On 172 hyperthermias observed, 49% were accompanied by a circulating parasitemia and 30% corresponded to malaria attack. The feverish subjects (74% vs. 42%), the subjects with parasitemia (51% vs. 16%) and the cases of malaria (34% vs. 10%) were more frequently encountered in children under10 than in the oldest. The cases of malaria attacks were more frequent from November to January (70%). The strong intensity of malaria transmission in Barkedji and the persistence of its temporary ponds until January were sufficient to influence the level of malaria morbidity and consequently the development of an anti-malaria immunity by the indigenous population.
Adolescent↗
Influence of glenohumeral mismatch on bone strains and implant displacements in implanted glenoïds. An in vitro experimental study on cadaveric scapulae.
In shoulder arthroplasty, there is no consensus about the ideal mismatch between a prosthetic humeral head and a glenoïd component. Thus, investigations into mismatch effects from a biomechanical point of view can be useful. The aim of this in vitro study was to help us understand mismatch influence on bone strains, translational forces in the joint and implant/bone displacements in implanted scapulae. Five fresh cadaveric scapulae were implanted with a cemented keeled polyethylene implant. The lower part of the scapulae was embedded and the loadings were carried out using five metallic spheres simulating mismatches of 0, 2, 4, 5 and 6 mm. Loadings included a constant compressive preload of 392N and an anterior, posterior, inferior and superior translation of 2.5 mm. We measured the transversal force necessary to produce the imposed translation, the strains at six locations around the peripheral cortex of the glenoïd using strain gages and the relative implant/bone displacements using CCD cameras. Generally, the increase of mismatch reduced the translational forces, the strains around the glenoïd and, except for the anterior loading, the relative implant/bone displacements. Few and even no significant differences were observed when the mismatch varied from 0 to 2 mm; the number of significant differences increased when the mismatch varied from 0 to 4mm and from 0 to 5 mm; the results obtained for a 0-6 mm variation in mismatch were comparable to those obtained for a 0-5 mm variation. This study underlines that the mismatch has a significant effect on bone strains, relative implant/bone displacements and induced translational forces when a compressive preload and imposed translations were applied on implanted scapulae.
Aged↗
A 3D finite element model of an implanted scapula: importance of a multiparametric validation using experimental data.
In order to help to understand the loosening phenomenon around glenoïd prostheses, a 3D finite element model of a previously tested implanted scapula has been developed. The construction of the model was done using CT scans of the tested scapula. Different bone material properties were tested and shell elements or 8 nodes hexaedric elements were used to model the cortical bone. Surface contact elements were introduced on one hand between the bone and the lower part of the plate of the implant, and on the other, between the loading metallic ball and the upper surface of the implant. The results of the model were compared with those issued from in vitro experiments carried out on the same scapula. The evaluation of the model was done for nine cases of loading of 500 N distributed on the implant, in terms of strains (principal strains of six spots around peripheral cortex of the glenoïd) and displacement of four points positioned on the implant. The best configuration of the model presented here, fits with experiments for most of the strains (difference lower than 150microdef) but it seems to be still too stiff (mainly in the lower part). Nevertheless, we want, in this paper, to underline the importance of doing a multiparametric validation for such a model. Indeed, some models can give correct results for one case of loading but bad results for another kind of loading, some others can give good results for one kind of compared parameters (like strains for instance) but bad results for the other one (like displacements).
Aged↗
[Complications of treatment of adult's groin hernia: a report of 100 cases comparative study between Bassini and Mac Vay's technics].
The authors report a prospective study comparing pre and immediate post operative complications of non complicated hernia of the groin in adult treated by operations based on Bassini and Mac Vay technics. It concerned a total of 100 patients made up of two groups of 50 age ranging from 13 to 84 years with an average age of 47 years of whom were 93 males and 7 females. No mortality was registered. The rate of complications was 20% in Bassini's technic and 22% in Mac Vay's technic. There were: bladder injurie, accidental skin wound incurred by the electric surgical blade, meningeal irritation, urinary retention, scrotal sac hematoma, parietal suppuration, intestinal occlusion and immediate recidivation before 6 months. As well as our study as in literature, specific complications related to both technics were rare. We could draw the conlusion that there is no significant superiority of one technic in comparison with the other one.
Adolescent↗
[Contribution to the study of the congenital anomalies at the Albert-Royer paediatric hospital of Dakar].
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Abnormalities, Multiple↗
[Apical foramen position on mesio buccal root of the maxillary first molar. Study in Senegalese population].
The maxillary first molar is submitted to frequent endodontic treatment and more over, it presents the highest failure rates, often in relation with his mesio-buccal root. Several studies about failures factors showed implication of root canal anatomy often in relation with the frequency of second canal. However, other failures factors, as the foramen situation, which is very important in endodontic practice, could increase the failure rate. The aim of this study was to determine the foramen situation in Senegalese people. The results showed 63.85% of excentric foramina (83 out of 130). 86% of excentric foramina were located at 1.5mm radiology apex.
Adolescent↗
In vitro biomechanical analysis of glenoïds before and after implantation of prosthetic components.
Biomechanical investigations are yet necessary to better understand the origin of the glenoïd loosening which is the main reason for revision surgery. The aim of this study was to analyse the behaviour of cadaveric glenoïds before and after implantation of glenoïd prostheses. For that, we developed a new experimental protocol allowing measurement of bone strains and implants displacements under various loading cases. Ten pairs of fresh cadaveric scapulae were tested. Two kinds of loads were applied on the intact glenoïd: physiological loads corresponding to a 0-180 degrees abduction and anteflexion movements, and 500N loads. The glenoïds were then implanted with a keeled or pegged cemented polyethylene implant. The same previous 500N loads were then applied on the implanted glenoïds. Strains were measured using six strain gages placed on precise points around the peripheral cortex of the glenoïd. Displacements of implants under loading were measured using two CCD cameras. Maximum strains were obtained between 60 degrees and 120 degrees of abduction or anteflexion. They were located at the anterior and antero-superior parts of the glenoïd during abduction and at the posterior and postero-superior parts during anteflexion. Implantation of a prosthetic component generally seemed to increase strains, but tensile strains were decreased at the postero-inferior part with the antero-inferior loading point.Some differences were observed between the implants, but they have to be confirmed by further experiments. The great number of data obtained for intact scapulae could be used for a better understanding of glenoïd behaviour and for validation of finite element models.
Aged↗
[Role of Anopheles melas Theobald (1903) on malaria transmission in a mangrove swamp in Saloum (Senegal)].
From June 1995 to January 1998, entomological studies carried out in five villages located in the Delta's Saloum have allowed to better understand the contribution of An. melas Theobald (1903) to malaria transmission in mangrove swamp. Among the five villages studied, three of them (Simal, Djilor and Marlothie) located along the Saloum river, are colonised by An. arabiensis; the two others (Djifere and Diakhanor) located between the sea and the river, are colonised by An. melas. During the rainy season and at the beginning of the dry season, An. melas and An. arabiensis are sympatric. The ratio of An. melas/An. arabiensis increases when we go closer the coast where An. melas becomes quite exclusive. When An. melas is predominant, endophagy, endophily and anthropophily are very marked. The parturity rates are lower in An. melas than in An. arabiensis. In the predominance area of each species, transmission is on the same level. During the period of sympatry, An. arabiensis is responsible for the transmission and when it is absent, An. melas carries on. Transmission occurs from July to March with a maximum at the beginning of the dry season. In the villages of the mangrove swamp, its prolongation until the middle of the dry season is due to An. melas.
Animals↗
[Long term course after thyroidectomy for euthyroid nodular goiter].
Every patient operated for nodular goiter by a partial surgery is exposed to recurrence. In order to verify this idea, the authors followed 36 patients operated on for nodulargoiterat least 10 years ago. A clinical examination for all the patients and echographic study for 24 of them allowed the detection of recurrence and the evaluation of survival and recurrence without any opotherapy. It seemed that clinical recurrence is observed in 16.65% of cases whereas echographic study revealed recurrence in 50% of patients examined. Only two patients were reoperated on. The predictive factors of the recurrence are geographic endemic origin and ethny, partial surgery and vesicular goiters. With 66.65% of survival without recurrence at 18 years without opotherapy, the authors argue about the utility of such treatment.
Adult↗
[Role of elastic compression in the treatment of postphlebitic leg ulcers at the University Hospital of Dakar: report of 20 cases].
Varicose disease and venous thrombosis were reputed exceptional among black africans and almost all leg ulcers were called "tropical". We have treated 20 cases of postphlebitic ulcers in the teaching hospital of Dakar between march 1989 and december 1992. There were 12 men and 8 women. Mean age was 40 years (24 to 60 years). The initial venous thrombosis dated at mean 8 +/- 3 years. It was confirmed in a hospital in 10 cases and found in the medical history of all patients. All patients presented leg ulcers with non systematised venous varicose and trophic troubles. The ulcers treated only by dressings lasted a duration of 4 months (2 weeks to 9 months) without healing. In view of this failure we have added an ambulatory elastic contention with elastic bandage putted on at hospital after that biweekly dressing until cicatrisation followed by putting elastic socking with degressive compression. We have observed a quickly cicatrisation in mean time of 4 weeks (2 to 6 weeks) with good tolerance of socking. Only 3 patients showed recurrence. Elastic contention has a great place in the treatment of postphlebitic ulcers which are not that exceptional among black Africans.
Adult↗
Comeback of Anopheles funestus in Sahelian Senegal.
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Animals↗
[Efficacy of the combination of DEET (20%) and EHD (15%) against mosquito bites. Results of a study carried out in Senegal].
The authors report the results of a survey on the efficacy against mosquito bites of a repellent, Mousticologne Spécial Zones Infestées (DEET 20%, EHD 15%). Two forms of the product, spray and gel, were tested in Senegal. Repellent efficacy was evaluated by exposing volunteers, both repellent-treated and untreated, to mosquito bites. The number of mosquito bites per person and per night was 0.63 in the spray treated group (group 1), 6.03 in the gel treated group (group 2) and 94.17 in the untreated group (group 3). The analysis of these results showed a significant difference between treated and untreated persons. Untreated persons were not protected against mosquito bites, persons treated with the spray were protected for 12 hours and those treated with the gel had over 8 hours' protection. We concluded that a single application of the repellent Mousticologne in the field is capable of ensuring all-night protection against mosquito bites.
Aerosols↗
An experimental study of ring avulsion injuries and two preventive devices.
We have performed biomechanical experiments on fresh cadaveric fingers to test two modifications to normal rings which may prevent ring avulsion injuries. One of these modifications produced reliable protection against ring avulsion accidents and was undetectable. It thus does not reduce the symbolic value of a wedding ring.
Aged↗
[Predictive ultrasonographic criteria for portal hypertension due to Schistosoma mansoni in a recently established endemiz zone].
The first cases of Schistosoma mansoni infection were reported in the Senegal River Basin ten years ago. Today endemicity is so high that prevalence rates exceed 90 p. 100 in some areas. Schistosomiasis sometimes goes undiagnosed until the occurrence of portal hypertension with rupture of esophageal varices. Endoscopy is the gold standard for detection of esophageal varices but it is impractical in remote areas. Ultrasonography has been proposed as a non-invasive alternative. The purpose of this study is to describe the results of simultaneous endoscopic and ultrasonographic assessment in 101 subjects from the Richard-Toll area of the Senegal River Basin. Findings showed that severe forms of schistosomiasis complicated by portal hypertension were already present in the region less 10 years after description of the first case. This study also proposes a diagnostic score for portal hypertension based on ultrasonographic findings. The features included in this score are thickening of portal vessel walls, portal vessel diameter, and collapsed appearance of the splenic vein during inspiration. In our hands this score allowed reliable prediction of the development of esophageal varices. Ultrasonography is a good tool for identifying severe forms of schistosomiasis. It should be useful for routine screening in recently established endemic zones.
Adolescent↗
[Lumbar hernia through the Jean Louis Petit triangle: anatomic and clinical aspects].
Lumbar hernia through Jean Louis Petit Triangles is rare. Usually asymptomatic, it is sometime revealed by lumbar mass or a complication. Surgical treatment consists on parietal repair. This could be done by direct suture, muscular plasty or prothetic material. We hereby, report three cases of lumbar hernia. We get the opportunity to make an update in the anatomical, clinical and therapeutical point to view.
Abdominal Muscles↗
[Interbody arthrodesis using a plasmapore titanium block. Mechanical and histological experimental study in sheep].
UNLABELLED: A Plasmapore-coated titanium alloy block was implanted in ewes for the purpose of providing interbody fusion. Four blocks were implanted in each ewe: one uncoated block (without Plasmapore) serving as a reference specimen and three blocks coated with Plasmapore. Mechanical testing and histological study were performed on five ewes. OBJECTIVES: Determination of the quality of the mechanical and histological anchorage of the Plasmapore implanted in the interbody space in the same animal living under conditions of physical strain exerted on the spine. METHODS: Four months after surgical implantation of the block, the ewes were sacrificed: the removed spines were frozen for subsequent mechanical analysis and preserved in a solution of 40 degrees alcohol for subsequent histological analysis. X-rays were taken to evaluate the positioning of the implant. The mechanical analysis included extraction tests, measuring the maximum extraction force and evaluating the stiffness of the system, being indicative of the mechanical fixation quality. The histological study included both qualitative and quantitative analysis, together with an evaluation of the osteointegration of the blocks coated with Plasmapore. RESULTS: After 4 months of implantation, a mean extraction force of 990 N was necessary for the blocks coated with Plasmapore, and of 1.338 N for the blocks coated with Plasmapore with additional osteosynthesis, whereas a mean extraction force of 332 N was necessary for the uncoated blocks. Anchorage and resistance against uprooting of the blocks coated with Plasmapore were significantly more efficient. The histological study revealed the presence of bone neoformation adhering to the implant. Quantification of this bone formation covering nearly 45% of the implant perimeter, confirmed both osteointegration of the implant perimeter, confirmed both osteointegration of the implant surfaces being in contact with the vertebral endplates and osteoconduction along the lateral surfaces. CONCLUSION: The titanium Plasmapore block enables interbody fusion due to an osteointegration of the vertebral endplates by Plasmapore coating, which was proved by the results of extraction testing and histological study. It should be taken into account that no additional bone grafts have been used and that the implant had not been forced into the spongiosa.
Animals↗