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Biomedical subjects

A Dodek

Publications and source records attributed to A Dodek.

At least 37 records · Page 2Linked to original sources

Hypertension in the runner.

A therapeutic game plan is important for the management of hypertension in the runner. Participation in physical training programs may result in lower resting blood pressure in mild hypertensives. Maximal exercise tests can be used to identify those hypertensive patients with a dangerously high exercise blood pressure. Most antihypertensive drugs can be used for the treatment of hypertension which is refractory to exercise training. Atenolol, a cardioselective beta blocker has minimal side effects and the least risk of impairing performance. Calcium channel blockers effectively lower exercise blood pressure and should be used when side effects of beta blockers contraindicate their use in patients.

Adrenergic beta-Antagonists↗

Chylopericardium in a drug addict.

Nontraumatic chylopericardium without chylothorax is rare. We describe a patient with chylopericardium associated with intravenous drug addiction. To our knowledge, this association has not been reported previously. The patient underwent total pericardiectomy and had had no recurrence 24 months after surgery.

Adult↗

Complications of coronary arteriography.

In a prospective study of coronary arteriography with Judkins' technique the rate of major complications in 713 patients was 2.1%, a rate similar to or lower than those reported from other studies, even though more major complications were considered in this study. No deaths occurred. Although the rate of "other" complications was noted as part of the quality care survey, it cannot be compared with that in other studies, since the latter did not consider events such as hematoma or incomplete catheterization. The low complication rate may be related to expeditious procedures, familiarity with the Judkin's technique and the operators' experience. Local quality care assessment or clinical review committees should formally evaluate the complication rates for operative and invasive procedures performed in their own institutions.

Angiography↗

Atrial septal defect in adult identical twins: a variation in theme.

The diagnosis of atrial septal defect was established in monozygotic twin females at age 63. Each patient mimicked a different acquired heart disease. One twin had congestive heart failure and atrial fibrillation and was diagnosed as having rheumatic mitral insufficiency. The other twin had atypical chest pain and systemic hypertension and was thought to have arteriosclerotic heart disease. In each case the correct diagnosis was made at cardiac catheterization. Although the same basic congenital heart lesion was present in both patients, the symptoms and findings differed. Symptomatic improvement was achieved by different therapeutic modalities. One patient had open heart surgery, while the other twin improved with medical therapy.

Cardiac Catheterization↗

Mitral valve prolapse in a runner.

In the past decade mitral valve prolapse has become a popular diagnosis. This may be related to the increased utilisation of cardiac ultrasound diagnostic techniques. Although many initial medical articles highlighted patients with complications of mitral valve prolapse, the natural history of isolated mitral systolic click is benign. Complications are sudden cardiac death, symptomatic cardiac arrhythmias, endocarditis, ruptured chordea tendinae, progressive mitral regurgitation, and cerebral ischemic events. However, these occur more likely in patients with MVP and associated mitral regurgitation and/or ECG repolarization abnormalities. The subject in this case example had nonanginal chest pain possibly related to silent mitral valve prolapse, documented on echocardiography. There is a coincidental finding of "athletic heart" on electrocardiogram. Stress ECG and thallium scintography showed excellent cardiorespiratory fitness and normal myocardial perfusion. He was given reassurance that there was no significant cardiac problem, and subsequently completed a marathon run without consequence.

Adult↗

Systolic time intervals in chronic hypertension: Alterations and response to treatment.

Systolic time interval studies were performed to evaluate left ventricular performance in 28 patients with untreated systemic hypertension but without clinical heart failure. The pre-ejection period (PEP) was significantly prolonged (p smaller than 0.001) and left ventricular ejectime time (LVET) was shortened (p smaller than 0.02) when compared to rate-corrected predicted values. The PEP/LVET ratio was abnormally high in 18 of the patients and the average ratio was 0.45 ( smaller than 0.001). Eleven patients with abnormal time intervals were restudied during treatment with antilypertensive drugs. The PEP/LVET raio decreased in ten and became normal in nine. The average ratio decreased from 0.49 to 0.41 (p smaller than 0.001), due to both shortening of PEP (p smaller than 0.02) and lengthening of LVET (p smaller than 0.001). These findings indicate that alterations in left ventricular function may occur commonly in chronic hypertension in the absence of clinical heart failure, and can be reversed with appropriate therapy. This technique may be useful in evaluating hypertensive patients and in determining the efficacy of treatment.

Adult↗

Digitalis use in acute myocardial infarction: current concepts.

Digitalis is one of the oldest and most commonly prescribed medications. There has been continuing controversy regarding its use in acute myocardial infarction. Recent information from animal experiments and clinical investigation serves as a guide for its appropriate use in this situation. When it is used appropriately and judiciously there is no increase in toxicity or cardiac arrhythmias. In fact, there is benefit to the patient who has a failing myocardium associated with acute myocardial infarction.

Animals↗