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A Domínguez García

Publications and source records attributed to A Domínguez García.

11 recordsLinked to original sources
PubMed2006

[Clinical and epidemiological characteristics of influenza A virus infection in children aged less than 7 years old in primary care].

INTRODUCTION: The aim of this study was to describe the clinical and epidemiological features of confirmed influenza A virus infection in patients aged less than 7 years old. PATIENTS AND METHODS: We performed a retrospective, descriptive study of the clinical and epidemiological features of influenza A virus infection in patients aged less than 7 years old attending three primary care centers during the 2003-2004 influenza season. Patients with influenza A infection confirmed by immunofluorescence, cell culture, or polymerase chain reaction were interviewed to obtain clinical and epidemiological data on their disease. RESULTS: Influenza A virus was detected in 47 patients aged between 5 months and 7 years (mean: 37.3 +/- 5.7 months). Of these, 35 children (74.4 %) were aged between 0 and 4 years. The most frequent symptoms were fever (100 %), cough (95.7 %), and rhinorrhea (76.6 %). Gastrointestinal symptoms were present in 40.4 % of the patients. The mean duration of fever was 5.2 +/- 1.8 days (range 2-8). Complications occurred in nine patients (19.2 %). The frequency of influenza-like disease in parents was 9.1 % (8/88) at diagnosis of the index case and was 23.9 % (21/88) immediately after the episode in the child (p 5 0.01). The mean number of days of absence from school was 7.5 +/- 3.6 days. CONCLUSIONS: The mean age of our patients confirms that influenza is a frequent disease in infancy and childhood. The results demonstrate that the infection is transmitted from children to parents in the household setting, since the frequency of influenza-like symptoms in adults increases after influenza episodes in children.

Child↗
PubMed2005

[Effects of HIV status and other variables on the outcome of tuberculosis treatment in Spain].

OBJECTIVE: To analyze the effect of human immunodeficiency virus (HIV) status and other variables on the outcome of tuberculosis treatment in Spain. PATIENTS AND METHODS: Multicenter retrospective cohort study in 6 autonomous communities of Spain (from May 1996 to April 1997). Data on treatment outcome were collected for new cases of tuberculosis in accordance with European guidelines. Follow up of patients continued for 3 months after scheduled end of treatment. RESULTS: Of the 4899 patients included, 3417 (69.7%) had a satisfactory outcome, 438 (8.9%) died before or during treatment, and 1044 (21.4%) had a potentially unsatisfactory outcome. On stratification by HIV status, satisfactory outcome, mortality, and potentially unsatisfactory outcome were reported for 43.4%, 21.5%, and 35.1%, respectively, of HIV-positive patients; 71%, 6.2%, and 22.8%, respectively, of HIV-negative patients; and 74.3%, 7.5%, and 18.2%, respectively, of patients with no HIV status available. HIV modified the effect of several variables on the outcome of treatment, and so separate logistic regression models for each HIV category were constructed. Among HIV-positive patients, mortality increased in patients with neoplastic disease and in users of drugs by nonintravenous routes of administration, whereas potentially unsatisfactory outcomes increased in intravenous drug users and in women. CONCLUSIONS: In Spain, the outcome of tuberculosis treatment is much worse in HIV-positive patients. Drug use and presence of neoplastic disease substantially affect mortality.

Adolescent↗
PubMed2001

[Results of anti-tuberculosis treatment in six autonomous regions in Spain].

BACKGROUND: To analyze tuberculosis treatment outcome in Spain. PATIENTS AND METHOD: A retrospective cohort study was performed of 6 Autonomous Regions of Spain: Asturias, Catalonia, Galicia, La Rioja, Murcia and Basque Country. Study subjects were new cases of tuberculosis identified through the MPTR who were not in prison at the time of diagnosis (May 1996-April 1997). Information was gathered from the patients' clinical records. Guidelines issued for tuberculosis treatment outcome monitoring in Europe were followed. RESULTS: A total of 4,899 new cases of tuberculosis met the criteria for inclusion. Out of them, 4,240 (86.6%) had enough information on tuberculosis treatment outcome in their clinical record. Results showed that 3,417 cases (69.7%) had a satisfactory outcome, 438 (8.9%) died before or during treatment and 1,044 (21.4%) met the definition of a potentially unsatisfactory outcome. There were important differences in treatment outcome between regions. There were also variations by nationality, age group, HIV status, history of intravenous drug use, history of alcohol abuse and site of disease. CONCLUSIONS: According to the results of our study, the proportion of new cases of tuberculosis that had a satisfactory outcome at the end of treatment do not reach WHO recommended level to effectively control the disease. Therefore, it is necessary to analyze the situation and to propose measures to improve it.

Adolescent↗
PubMed1983

[Not Available].

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Anatomy↗
PubMedDate not supplied

[Evaluation of the information provided by the system of compulsory notification of diseases].

In order to assess activities of epidemiological surveillance resulting from the statutory notification system, a total of 17,394 notification records of eight infectious diseases (brucellosis, bacillary dysentery, typhoid fever, viral hepatitis, meningococcal infection, rickettsioses other than exanthematous typhus, pulmonary tuberculosis, and tuberculosis of other organs) together with 10,503 epidemiological surveys submitted to the "Servei Territorial de Salut Pública" of the province of Barcelona between 1982 and 1986 were reviewed. In notification records, data to locate physicians were the most commonly found (between 92.6% and 99.4% according to disease), whereas in epidemiological surveys, clinical and analytical data were the most frequently encountered. The inclusion of data of epidemiological interest ranged from 3.6 to 68.6%. In order to improve efficacy of the statutory notification system a proposal is made to reduce the extension of epidemiological surveys in terms of requesting only necessary data to establish appropriate measures in each case.

Communicable Disease Control↗
PubMedDate not supplied

[Measles outbreaks: considerations apropos of the outbreaks investigated in Catalonia (1990-1995)].

OBJECTIVES: To determine the factors associated with outbreak size in Catalonia. METHODS: Outbreaks over the period 1990-95 were investigated. A comparison was run between outbreaks of more than 6 cases with respect to outbreaks of 2-6 cases in function of the following variables: median age of cases, transmission setting and year of presentation. Multiple logistic regression was used to asses the independent effect of each variable, with the adjusted odds ratio (ORa) and their 95% confidence interval (CI) being obtained. RESULTS: In all, 45 outbreaks were studied, with 595 cases of measles 39.5% of outbreaks occurred in the 6-10 age group. Outbreaks of more than 6 cases had a higher likelihood of appearing in a school setting (ORa = 4.3, CI 95% 1.0-17.6); but there were no association with age (ORa = 2.1, CI 95% 0.5-9.2) or occurring prior to 1994 (ORa = 0.9, CI 95% 0.2-3.6). CONCLUSIONS: School setting determines the outbreak size of measles and demands to apply specific preventive strategies.

Adolescent↗