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Biomedical subjects

A Dooms-Goossens

Publications and source records attributed to A Dooms-Goossens.

At least 91 records · Page 5Linked to original sources
PubMed1987

Contact and photocontact sensitivity problems associated with thiourea and its derivatives: a review of the literature and case reports.

Thiourea and its derivatives have been widely used in industry since the beginning of this century, but it was only in the late 1960s that reports of cases of contact dermatitis to these compounds began to appear in the literature. This literature is reviewed. We have observed eight cases of diphenylthiourea sensitivity in patients sensitive to adhesive tape. Four cases are presented of sensitivity to thiourea compounds in diazo-sensitized paper. Three of these patients were contact allergic to dimethylthiourea, and the other was contact and photocontact allergic to thiourea. These skin problems were mainly induced by airborne contact.

Adult↗
PubMed1987

Contact dermatitis. A review.

In recent years, there has been a dramatic rise in our understanding of contact dermatitis. This paper is a review of our knowledge of the mechanisms involved in contact dermatitis and related phenomena, the investigation of these events and the emergence of significant new allergens during the last 5 years.

Allergens↗
PubMed1987

Cosmetic intolerance.

A study of cosmetic intolerance has been undertaken in 5202 patients tested for possible contact dermatitis. Each patient has been evaluated by medical history and patch testing. Intolerance to cosmetics involved only 5.9% of the total population tested. If other possible sources of allergens (medication, occupation, hobbies etc) are associated, this figure rises to 11.7%. The origin of the cosmetic intolerance is more often an allergy than irritation. Soaps and shampoos are the most important types of cosmetics responsible for adverse reactions. The principal allergens are the fragrances, preservatives, hair dyes and the patients' own products. In this last category, the specific allergen has not always been detected.

Adult↗
PubMed1986

Contact allergy to hydrocortisone and thixocortol pivalate: problems in the detection of corticosteroid sensitivity.

Several of the difficulties involved in the detection of corticosteroid allergy are illustrated by the problems encountered in a patient sensitive to a preparation containing hydrocortisone and miconazole nitrate. The importance of appropriate concentrations and vehicles for patch testing, the possible rôle of impurities, and cross-sensitivity of corticosteroid molecules are discussed.

Administration, Topical↗
PubMed1986

Mercury intoxication after topical application of a metallic mercury ointment.

Two cases of mercury poisoning with predominantly dermatological symptoms are reported. The mercury intoxication was caused by the application of an over-the-counter metallic mercury ointment. The calculations of mercury excretion suggest strongly that cutaneous absorption could have been a significant route of entry.

Administration, Topical↗
PubMed1985

Patch testing with silver sulfadiazine cream.

23 patients who had used silver sulfadiazine cream were patch tested. No reactions to the active principle occurred but 2 vehicle components, cetyl alcohol and propylene glycol, were positive. No sulfonamide-sensitive subject reacted to silver sulfadiazine. There is no evidence that silver sulfadiazine has a contact sensitizing potential or that it is contra-indicated for patients with a history of sulfonamide hypersensitivity.

Cross Reactions↗
PubMed1985

Pustular reactions to hexafluorosilicate in foam rubber.

A case is reported of a foam rubber carrier with pustular lesions on the arms, wrists, thighs and trunk. Scratch and patch testing with the foam rubber components was negative. Animal testing revealed sodium hexafluorosilicate (Na2SiF6), one of the ingredients of the foam rubber, to be a pustulogen on previously damaged skin.

Adult↗