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Biomedical subjects

A Dreher

Publications and source records attributed to A Dreher.

22 records · Page 2Linked to original sources
PubMed1995

[Malignant melanomas of the nasal cavity and paranasal sinuses].

Mucosal melanomas of the nose and paranasal sinuses are rate tumours (2.4-4% of all malignancies in this area) with a poor prognosis. The increasing number of cutaneous melanomas during the last decades gave rise to determine the occurrence of mucosal melanomas of the nose and paranasal sinuses in our department between 1987-92. During this time, 6 patients with malignant melanoma of the nose and paranasal sinuses were seen in our department, representing 11% of all patients (55) with malignant tumours in this region. In five cases surgery was performed (with two patients receiving postoperative radiotherapy); one patient was treated primarily with irradiation. The mean survival time was only 19 months, which--from the authors' point of view--was mainly due to the extension of the tumours. The findings of this study might indicate an increase of malignant melanomas of the nose and paranasal sinuses; however, the number of patients is too small for a final statement on this matter.

Aged↗
PubMed1995

[Fordyce spots. A little regarded finding in the area of lip pigmentation and mouth mucosa].

Sebaceous glands on the vermilion border of the lips and the oral mucosa are common in adults. Only pathologic sebaceous glands visible through the epithelium should be regarded as Fordyce's granules. The incidence of Fordyce's granules increases from childhood to adulthood, and is slightly higher in men. The most prevalent sites are the vermilion border of the lips and the buccal mucosa. Fordyce's granules usually have the same histological features as cutaneous sebaceous glands. Pathologic alterations are rare. There is no significant correlation between Fordyce's granules and systemic diseases.

Adolescent↗
PubMed1978

[Influence of temperature on blood coagulation in vitro (author's transl)].

The influence of different temperatures between 13 degrees C and 45 degrees C on coagulation factors in vitro was studied by measuring clotting time with the recalcification time, partial thromboplastin time (PTT), and thromboplastin time test. In all three tests the shortest clotting times were measured at a temperature of 40 degrees C. The relation between temperature and clotting time was similar in fresh plasma and in plasma which had been stored at a temperature of --20 degrees C before examination. However, in all tests stored plasma showed shorter coagulation times. Prolongation of coagulation time at 45 degrees C is caused by irreversible reduction of coagulation activity in the plasma. At the same time thromboplastin- and PTT-reagent are imparied in their coagulation acitvity by a temperature of 45 decrees C. In comparison to plasma obtained from healthy persons plasma from patients with hemophilia A or B or with v. Willebrand's disease reacted more sensitive to changes in temperature in the PTT test. The coagulation defect was definitely more pronounced at 27 degrees and 17 degrees C than at 37 degrees C. It was not possible to differentiate these three coagulopathies with the PTT test at 27 degrees and 17 degrees C.

Blood Coagulation↗