Favourable outcome of a brain trauma patient despite bilateral loss of cortical somatosensory evoked potential during thiopental sedation.
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Adult↗
Biomedical subjects
A Dubuisson
Publications and source records attributed to A Dubuisson.
[Thoracic outlet syndrome].
Thoracic outlet syndrome (TOS) is due to compression/irritation of brachial plexus elements ("neurogenic TOS") and/or subclavian vessels ("vascular TOS") in their passage from the cervical area toward the axilla. The usual site of entrapment is the interscalenic triangle. TOS is a highly controversial subject in regard to its incidence, diagnostic criteria and optimal treatment. Constitutional factors--osseous or more often fibromuscular--and external factors such as trauma predispose to the development of TOS. Various clinical pictures include pain in the cervical region and arm, paresthesias, aggravated by overhead positions of the arms, hand intrinsic muscle deficit/atrophy, easy fatiguability, paleness, coldness of hand. The clinical examination may be entirely normal or show cervical and scapular muscle spasm, tenderness of supraclavicular area, radial pulse attenuation upon positional maneuvers, sensory and/or motor deficit, usually of C8/T1 distribution. The diagnosis is based on clinical evaluation and absence of other relevant pathology. Sometimes TOS can enhance symptoms consecutive to cervical or supraclavicular lesions. Cervical spine and distal peripheral nerves are investigated by radiological and electrophysiological studies. Unless there is significant motor deficit or subclavian artery compression, the treatment should be kept conservative as long as possible, by adapted physical therapy. In case of neurological deficit or symptoms unresponsive to medical treatment, the patients will--like in other nerve entrapment syndromes--be helped by decompressive surgery, nowadays preferably performed via an anterior supraclavicular approach.
Brachial Plexus↗
Sciatic nerve regeneration through venous or nervous grafts in the rat.
This study analyses the interest of isologous venous grafts filled with saline or with Schwann cells versus nerve grafts as guides for regeneration of the sciatic nerve in 35 Wistar rats. Electrophysiological parameters (conduction velocities and distal latencies of motor responses) and the functional index of De Medinacelli were measured several times from 1 month to 1 year after surgery. An histological analysis was performed on 2 control rats and on 3 rats killed 6 or 12 months after surgery: the total number of fibers was counted on a montage photoprint of the whole nerve, and the diameters of axons and the thickness of the myelin sheath were measured on digitized images. With a portion of nerve as guide, the regeneration is faster than with a vein. However, regeneration after 6 months is at least as good with a venous graft filled with Schwann cells, as assessed by electrophysiological, functional, and histological analysis. The addition of Schwann cells in grafted veins allows the nerve to regenerate through longer gaps than previously described (25 vs 15 mm). In order to assess the quality of nerve regeneration, functional, electrophysiological, and histological analysis are complementary.
Animals↗
[Foot drop. A differential diagnosis problem].
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Adult↗
[Meralgia paresthetica].
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Femoral Nerve↗
Soft cervical disc herniation: a retrospective study of 100 cases.
During the period from January 1975 to January 1991, 100 patients with soft cervical disc herniation were operated on by either the anterior (84 patients) or posterior (16 patients) approach. There were 33 women and 67 men, aged from 25 to 67 years (average: 41.5%); 97% presented with radicular symptoms and/or signs while 15% presented with long tract symptoms and/or signs. The patients were evaluated by computed tomography and/or myelography. Thirty-six of the lesions occurred at the C 5/6 level and 54% at the C 6/7 level. Seventy-seven % reported total or partial relief of preoperative symptoms and signs postoperatively. Patients presenting with radiculopathy had better outcome than those presenting with combined radicular and spinal cord involvement.
Adult↗
Indications for peripheral nerve and brachial plexus surgery.
Management of peripheral nerve injuries differs depending on the mechanism of injury. 1. If a nerve has been sharply and completely transected, it should be acutely repaired, especially if proximally located. 2. If a nerve has been bluntly divided and the stumps are found to be bruised, they should be tacked to adjacent planes. A secondary repair at 2 to 4 weeks is then recommended. 3. With closed injury in which the nerve is most likely still in continuity, the patient should be followed clinically and electrically for 2 to 5 months, depending on the nerve involved and the mechanism of injury. If there is no reversal of the proximal portion of the neurologic deficit by that time, surgical exploration should be done. Use of intraoperative NAP testing is important in this large category of injuries. 4. Injection and electrical injuries to a nerve are two special categories of lesions in continuity and require a highly specialized and individualized treatment dependent on the degree of deficit and severity of pain. 5. Pain unresponsive to medical treatment may also be an indication for surgery on a peripheral nerve, especially if the injured nerve needs to be repaired because of persistent neurologic loss. 6. Management of brachial plexus injuries is somewhat different. Function of each element of the plexus has to be analyzed separately. Several clinical, electrical, and radiologic findings may provide important information about how proximal the lesion is. 7. Missile wounds usually leave the nerve in continuity. Initial management is surgically conservative. Nonetheless, many of these lesions will subsequently require resection based on NAP recordings. 8. Management of obstetric brachial plexus palsy is controversial. We recommend initial conservative management, with observation much longer (9 to 12 months) than for other stretch injuries occurring in adults. With this approach, some but not many of such injuries will still need repair.
Brachial Plexus↗
A benign tumor of the sciatic nerve: case report and review of the literature.
Tumors arising from the sciatic nerve are a rare occurrence. A case is described of such a tumor developing as a large painless mass in the posterior right midthigh. The preoperative diagnosis was easily achieved by means of ultrasonography and computed tomography. Excision of the tumor, with preservation of the involved nerve, was performed. Microscopic examination showed a neurofibroma with however some features of a schwannoma. Problems of histological diagnosis and treatment are emphasized.
Diagnostic Imaging↗