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Biomedical subjects

A E Bacevice

Publications and source records attributed to A E Bacevice.

6 recordsLinked to original sources

Effects of pregnancy on the electrocardiogram in healthy subjects during strenuous exercise.

OBJECTIVE: Our purpose was to examine the nature and the frequency of electrocardiographic changes at rest and after bicycle exercise in early and late gestation compared with a group of nonpregnant subjects. STUDY DESIGN: Thirty-nine pregnant subjects had electrically braked bicycle exercise early and late in gestation. Eight nonpregnant subjects served as controls. Twelve-lead electrocardiograms were obtained during rest, exercise, and recovery. All electrocardiograms were analyzed by a cardiologist blinded to subject group and stage of the pregnancy. Data were analyzed by analysis of variance for repeated measures, and contingency tables were used to compare findings at rest and during exercise between the time periods. A p value < 0.05 was considered significant. RESULTS: T-wave inversion in V2 was more frequent in the pregnant than the nonpregnant subjects (p < 0.01). Subjects "late" in pregnancy had significantly fewer Q waves in II, III, and aVF than the nonpregnant group did. With exercise the time to onset of maximum ST depression was significantly shorter during pregnancy. CONCLUSION: Although minor electrocardiographic charges were found at rest and during exercise between the two groups, these should be considered normal unless associated with significant symptoms.

Adult↗

Umbilical artery waveform during bicycle exercise in normal pregnancy.

Eighteen healthy pregnant women in the last half of gestation exercised to 85% of their predicted maximum heart rate on a bicycle ergometer. Pulsed Doppler flow studies before the exercise and during the recovery period were taken close to the umbilical artery's placental insertion site. The systolic-to-diastolic ratio (S/D) of the umbilical artery waveform did not change significantly during the period of observation. In three women, however, a significant increase in the S/D ratio occurred in the first few minutes post-exercise; this was due to a transient fetal bradycardia. In one woman, the S/D ratio remained high despite return of a normal fetal heart rate.

Adult↗

Computer analysis of slow vital capacity spirograms.

We have developed a digital computer program which evaluates the vital capacity and its subdivisions, expiratory reserve volume and inspiratory capacity. The algorithm examines the multibreath spirogram, a continuous record of quiet breathing interspersed among repeated slow, large volume maneuvers. Quiet breaths are recognized by comparing features of each breath to the respective average and variation of these features for all breaths. A self-scaling, iterative procedure is used to identify those end-tidal points that most likely represent the subject's functional residual capacity. A least-squared error baseline is then fit through these points to partition the vital capacity. Twenty-three spirograms from patients with documented pulmonary disease were independently analyzed by the computer, a pulmonary function technician, and the laboratory supervisor. No practical differences were found among the results. However, the computer's values, in contrast to those of the technician, were reproducible on repeated trials and free of computational and transcriptional errors.

Computers↗