Biomedical subjects

A E Hosoi

Publications and source records attributed to A E Hosoi.

4 recordsLinked to original sources

PubMed2005

Two-dimensional self-assembly in diblock copolymers.

Diblock copolymers confined to a two-dimensional surface may produce uniform features of macromolecular dimensions (approximately 10-100 nm). We present a mathematical model for nanoscale pattern formation in such polymers that captures the dynamic evolution of a solution of poly(styrene)-b-poly(ethylene oxide), PS-b-PEO, in solvent at an air-water interface. The model has no fitting parameters and incorporates the effects of surface tension gradients, entanglement or vitrification, and diffusion. The resultant morphologies are quantitatively compared with experimental data.

Journal Article↗

PubMed2005

Theory for shock dynamics in particle-laden thin films.

We present a theory to explain the emergence of a particle-rich ridge observed experimentally in a thin film particle-laden flow on an incline. We derive a lubrication theory for this system which is qualitatively compared to preliminary experimental data. The ridge formation arises from the creation of two shocks due to the differential transport rates of fluid and particles. This parallels recent findings of double shocks in thermal-gravity-driven flow [A. L. Bertozzi, Phys. Rev. Lett. 81, 5169 (1998); J. Sur, Phys. Rev. Lett. 90, 126105 (2003); A. Munch, Phys. Rev. Lett. 91, 016105 (2003)]. However, here the emergence of the shocks arises from a new mechanism involving the settling rates of the species.

Models, Theoretical↗

PubMed2004

Peeling, healing, and bursting in a lubricated elastic sheet.

We consider the dynamics of an elastic sheet lubricated by the flow of a thin layer of fluid that separates it from a rigid wall. By considering long wavelength deformations of the sheet, we derive an evolution equation for its motion, accounting for the effects of elastic bending, viscous lubrication, and body forces. We then analyze various steady and unsteady problems for the sheet, such as peeling, healing, levitating, and bursting, using a combination of numerical simulation and dimensional analysis. On the macroscale, we corroborate our theory with a simple experiment, and, on the microscale, we analyze an oscillatory valve that can transform a continuous stream of fluid into a series of discrete pulses.

Journal Article↗

PubMed2004

Periodic knolls and valleys: coexistence of solid and liquid states in granular suspensions.

We report the spontaneous emergence of a doubly periodic train of sedimented knolls in a dense suspension. These solidified knolls rise out of, and coexist alongside, a sea of freely flowing liquid in a slowly rotating horizontal bottle. We apply a variable viscosity model that permits simultaneous analysis of fluidlike and solidlike behaviors that are ubiquitous in a variety of sedimenting flows. The model generates qualitative agreement with experiments, and produces new insights into mechanisms by which sedimented structures form.

Journal Article↗