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Biomedical subjects

A E Lindner

Publications and source records attributed to A E Lindner.

At least 19 recordsLinked to original sources

Inflammatory bowel disease in the elderly.

Inflammatory bowel disease exhibits a bimodality in age-specific incidence rates, with the second peak occurring from 60 to 70 years of age. In the elderly, both ulcerative colitis and Crohn's disease tend to involve the left side of the colon. The course of disease and the basic principles of management in geriatric populations do not differ from those in younger patients; however, elderly patients do pose distinct problems in differential diagnosis and in therapy choice.

Aged

Mesenteric fat necrosis simulating a carcinoma of the cecum.

Fat necrosis in the mesentery is an unusual complication of an adjacent inflammatory process. This report demonstrates a case of fat necrosis resulting in multiple irregularly firm masses measuring up to 4.5 cm. in diameter which produced extrinsic pressure on the cecum and ascending colon, simulating a carcinoma radiographically and at surgery. The fat necrosis was caused by chronic appendicitis in association with pylephlebitis.

Aged

Lymphoreticular disorders of the gastrointestinal tract: roentgenographic features.

Recent advances have permitted close correlation of characteristic roentgen signs with the pathophysiologic alterations in lymphoreticular disorders of the gastrointestinal tract. The background of primary and secondary immunoglobin disorders with gastrointestinal manifestations is reviewed. The roentgenographic alterations in the small bowel of the enteropathic immunoglobulin deficiency syndromes and in lymphoma of the small bowel, stomach, and colon are discussed and illustrated in detail.

Agammaglobulinemia

Pneumatosis cystoides coli.

Pneumatosis cystoides coli in most cases is a disease of unknown etiology. In a few patients, it is secondary to an infarction or ulcerative colitis. Associated pulmonary emphysema is not uncommon. The gas pockets, whcih may be of varying size, can be identified along the contour of the bowel. The left side of the colon is more frequently involved than the right. The lesion is usually segmental. The rectum is almost always spared. Symptoms are negligible and operation is not required.

Colonic Diseases

The radiology corner: metastasis to the colon.

This case serves to illustrate the multiple routes which may occur in the dissemination of carcinoma of the stomach of the large bowel. Spread along the gastrocolic ligament involves the superior aspect of the transverse colon with limitation laterally by the phrenicocolic ligament. Once ascites has developed there is spread along the superior border of the sigmoid and lateral margin of the right side of the colon.

Colonic Neoplasms

The radiology corner: the small bowel in immunoglobulin deficiency syndromes.

Recent advances in immunology have permitted recognition of a group of patients who have gastrointestinal manifestations as part of an immunoglobulin deficency syndrome. Such immunoglobulin deficiency may be primary or may be secondary to a variety of diseases. We have classified and described the small bowel roentgen features associated with the various immunoglobulin deficiency syndromes as follows: 1. the sprue pattern, as seen in hypogammaglobulinemic sprue and in Ig-A deficient sprue; 2. multiple nodular defects; 3. inflammatory changes secondary to giardiasis, associated with immune deficiency diseases; 4. thickening of the small intestinal folds, as seen in the plasma cell dyscrasias, lymphoma, intestinal lymphangiectasia and amyloidosis.

Agammaglobulinemia