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Biomedical subjects

A E Merriam

Publications and source records attributed to A E Merriam.

26 records · Page 2Linked to original sources
PubMed1988

Atypical psychosis with disseminated subpial demyelination.

A 34-year-old woman experienced three episodes of an atypical psychosis, characterized by confusion, agitation, delusional thinking, paranoid ideation, and auditory hallucinations, during the 14 months prior to her death. Findings of gross examination of the brain and spinal cord were unremarkable. Histologic examination revealed scattered subpial foci of demyelination throughout the brain stem, with involvement of the hippocampal formation bilaterally. Although occasional active lesions at early stages of development were noted, most lesions were gliotic and therefore quiescent. This case and one similar example of disseminated subpial demyelination found in the literature probably represent an unusual variant of multiple sclerosis.

Adult↗
PubMed1988

The psychiatric symptoms of Alzheimer's disease.

The authors used a semistructured interview administered to primary family caregivers to assess the prevalence and nature of psychiatric pathology in 175 well-diagnosed community-residing Alzheimer's disease patients. Symptoms that are indicative of depression in the cognitively intact were virtually ubiquitous in this demented population. A variety of psychotic features were also regularly reported. The implications of these findings for the recognition and treatment of reversible psychiatric impairment are discussed.

Aged↗
PubMed1987

Corpus callosum function in schizophrenia: a neuropsychological assessment of interhemispheric information processing.

Impaired corpus callosum function has been reported in schizophrenia. We measured intra- and interhemispheric visual information processing in 16 schizophrenic patients and 16 matched controls. Although the schizophrenics performed worse between than within cerebral hemispheres, this pattern was similar to that of the normal controls. Schizophrenics do not show particular dysfunction of the corpus callosum.

Adult↗