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Biomedical subjects

A E Pashchenko

Publications and source records attributed to A E Pashchenko.

At least 19 recordsLinked to original sources
PubMed1988

[Free amino acids and the total middle molecule fraction of the blood serum in patients with continuously progressive paranoid schizophrenia undergoing treatment].

The authors have investigated the levels of free amino acids and of the total fraction of medium molecules in the blood serum of patients with the paranoid form of continuously progressive schizophrenia. It has been demonstrated that these parameters are different in clinically normal individuals versus schizophrenics. The concentrations of free amino acids were the highest in people aged 40 to 50 years (Cys, Ala, Lys, Asp, Thr, Tyr, Try, Val, Leu, Ile) being considerably lower in individuals aged 50 to 60 years (Cys, Ala, Tyr) and over 60 years (Lys, His, Asp, Tyr, Try) which corresponds to the highest activity of the process in patients aged 40 to 50 years and its stabilization in older age.

Adult↗
PubMed1983

[Age-related changes in the tissue content of total iodine, its hormonal and nonhormonal compounds and their metabolic course].

By the spectrophotometric method the age changes of total iodine content, its hormonal and non-hormonal compounds in rats and men tissues (muscles, liver, kidney, heart, lungs, brain, spleen and blood) have been studied. It was established that the total iodine content decreased at the expense of the protein-bound iodine concentration and also of the butyl-alcohol extractable iodine. The exchange of thyroid hormones intensity lowered.

Adult↗
PubMed1981

[Participation of the thyroid gland in the mechanism of development of cerebral circulatory disorders (clinico-experimental study)].

Experiments on 30 rabbits, as well as clinical studies on 180 patients with cerebral circulation disorders were carried out. It was found that in patients with hypertensive disease complication, thyroid hyperactivity was observed only in the age group of 35 to 45 years. It was also found that in the patients with hypertensive disease and the complications of the latter, repeated stresses intensified the neurosecretory functions of the hypophysis and the hypothalamus: this, in its turn, influenced the hormone-synthetizing function of the thyroid. The chronic hyperthyroid syndrome present in those patients led to an increased oxygen consumption by tissues, slowed down the electron transport along the respiratory chain, increased the content of iodine and protein, and intensified the effects of pressor agents, i. e. aggravated the symptoms of the hypertensive disease. All those factors play a definite role in the mechanism of the development of the cerebral circulation disorders in hypertensive patients.

Adult↗
PubMed1978

[Role of thyroid gland dysfunction in the pathogenesis and course of cerebral circulatory disorders].

The functional state of the thyroid gland was studied in 160 patients with different forms of disturbed cerebral circulation. The observations included studies of the iodine content and its fractions in the blood serum and a scanning of the thyroid gland. The author established the significance of thyroid gland dysfunction in the pathogenesis of hypertensive disease and cerebro-vascular insufficiency. In patients with hypertensive crises these studies detected the existence of a hyperthyroid syndrome. It was also found that in patients with cerebrovascular insufficiency accompanied by thyroid gland dysfunctions the clinical picture becomes more aggravated.

Cerebral Hemorrhage↗