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Biomedical subjects

A E Vermel'

Publications and source records attributed to A E Vermel'.

At least 37 records · Page 2Linked to original sources

[Metabolic status in workers engaged in the production of cobalt-containing powder compositions of hard alloys].

A wide-range complex of biochemical techniques was used to study metabolic processes in workers exposed to cobalt and ethanol. In practically healthy workers were found laboratory manifestations of hepato-biliary irritations, hyperpermeability of the hepatocytes' cytoplasmic membrane, cholestasis syndrome, initial manifestations of muscular dystrophy and minor signs of atherosclerosis risks. The biochemical shifts were like those in alcoholism cases. It was suggested that, under the existing technological conditions of cobalt-containing hard-facing alloys' powder processing, the action of ethanol increased the toxic effect of cobalt.

Adult↗

[Cobalt-induced cardiomyopathy in workers engaged in the manufacture of hard alloys].

Four male patients aged 32 to 42 years were followed up. The clinical picture of the disease was typical of dilated (congestive) cardiomyopathy with a subacute onset, development of pronounced heart failure; all the patients were found to have exudate pericarditis. All the men were of the same occupation; they worked at the hard alloy works at a bay of wet grinding in ethanol of metallic Co and hard alloy carbides. The content of Co in the air of the working premises exceeded the MAC and amounted to 7.8-10 mg/m3. Besides, 47 workers of the same occupation (90% of the number of persons engaged in making up powdered compositions of hard alloys) were examined in addition. 16 persons showed the signs of alcoholization, including 9 (out of 11) working at a bay of wet grinding. During the recent 20 years, no cases of respiratory occupational diseases were recorded at the bay. The cardiotoxic properties of Co manifest themselves after the preceding toxic exposures, among which the leading part is played by alcohol. Of the 4 patients, 3 developed the disease in the presence of alcoholism, in 1 patient, it was coupled with tuberculous intoxication. Marked tendency towards polycythemia and increase of the content of hemoglobin was a frequently occurring manifestation of Co action on the workers (rather than a sign of intoxication).

Adult↗

[Intensity of industrial noise and the incidence of arterial hypertension (according to data from a prospective epidemiological study of organized female populations in Moscow].

A prospective epidemiological study of women at textile mills (a study group) working under the conditions of intense industrial noise (85-105 dBA) and at bakeries without such noise (a control group) was conducted. In the study group 353 (80%) women and 450 (71%) controls were repeatedly examined after 4.9 and 4.2 yrs, respectively. In the presence of such factors as borderline AH, smoking, aggravated heredity with respect to AH, MI and cerebral stroke, noise increased 3-fold, on an average, the risk of AH development as compared to its absence. Therefore noise can be defined as a "decisive" factor for the action of other AH risk factors.

Adolescent↗

[Prevalence of arterial hypertension, ischemic heart disease and their risk factors in geologists in various regions of the USSR].

The authors presented the results of an epidemiological survey conducted simultaneously for the first time among persons of geological professions in order to reveal the prevalence of arterial hypertension (AH) and coronary heart disease (CHD) with account of labor intensity, climatic and geographic factors. Altogether 1041 men were examined in 4 regions: in Vorkuta (a trans-polar region), Ukhta (a northern region), Chita and the Central region. The highest AH prevalence was detected in Vorkuta (27.4%), the lowest--in the Central region; the highest CHD prevalence was noted in Ukhta, the lowest--in Vorkuta. As for labor intensity, persons whose work was characterized by psychologic stress, suffered from AH and CHD more frequently. Significant differences in the prevalence of these diseases were revealed among managers and employees.

Adult↗

[Effect of industrial noise on the prevalence of arterial hypertension].

Women exposed to industrial noise were subjected to a one-stage overall examination. The levels and character of industrial noise, microclimate, labour tension and the scope of physical activity had been evaluated before. Altogether 1584 women aged 17-55 years were examined to form 4 groups to be compared. The prevalence of arterial hypertension (AH) was found to be slightly higher in women exposed to the noise 90-100 dBA. It was shown by the method of the purposeful pair matching that the probability of an increase in the incidence of AH under exposure to industrial noise in the absence of other risk factors is 1.1--=1.9%; when combined with one of the factors such as overweight, aggravated heredity or aggravated obstetrical-gynecological anamnesis it rises up to 15%.

Adolescent↗

[Morphofunctional characteristics of the gastric mucosa in subacute local irradiation of the lumbar-aortic region in lymphogranulomatosis].

A decrease in acid secretion by gastric mucosa was registered 10-14 days after irradiation of the lumbal area in six patients with lymphogranulomatosis who were examined before irradiation, 10-14 days and 3-3.5 months after irradiation. Acid production indices came back to normal 3-3.5 months after irradiation. No changes were revealed in gastric mucosa by morphological examination either before or after irradiation. It is suggested that the decrease in acid secretion is due to functional changes in the stomach in response to irradiation.

Adolescent↗