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Biomedical subjects

A E Willner

Publications and source records attributed to A E Willner.

13 recordsLinked to original sources
PubMed1983

Cognitive dysfunction and tardive dyskinesia.

From a prospective study of tardive dyskinesia (TD), psychiatric patients with neuroleptically-induced "persistent" TD were contrasted with controls on a neuropsychological measure of abstracting ability. A significant association is demonstrated between impaired cognitive performance and TD, even when the neuropsychological measure was obtained in advance of TD onset.

Aged↗
PubMed1976

Analogical reasoning and postoperative outcome. Predictions for patients scheduled for open heart surgery.

We investigated whether postoperative outcome of open heart surgery is related to preoperative cognitive dysfunction. Patients ill enough to require open heart surgery frequently have gravely compromised circulation and, hence, possible brain damage. The Conceptual Level Analogy Test (CLAT), a new, rigorously constructed analogy test, was used to measure cognitive dysfunction. The results indicated that the CLAT, aministered preoperatively to open heart surgery patients, differentiated between patients having different types of postoperative outcome. A significant relationship between type of surgical procedure and poor postoperative outcome was also found; cardiac valvular surgery patients had significantly worse outcome than coronary bypass surgery patients. The incidence of good outcome (survival with no psychiatric complications) was 28% for cardiac valvular surgery patients with extremely poor preoperative CLAT scores, but 74% for valvular surgery patients with higher preoperative CLAT scores.

Cardiac Surgical Procedures↗
PubMed1976

Psychopathology observed on follow-up after coronary bypass surgery.

Forty-six of 51 coronary bypass patients whose inhospital postoperative adjustment was reported earlier, were studied about 18 months postoperatively. In addition, 32 of 46 cardiac valvular surgery patients were seen as a comparison group. The incidence of postoperative psychiatric symptoms observed in the hospital, eight of 51 (16 per cent), and on follow-up, seven of 46 (15 per cent), was very similar; however, the patients who had these psychiatric symptoms comprised two almost entirely different groups. There were no indications that patients who developed psychiatric symptoms in the immediate postoperative period than patients asymptomatic postoperatively. There was a significant relationship between preoperative psychiatric illness and symptoms in the follow-up period.

Aged↗
PubMed1976

Analogy tests and psychopathology at follow-up after open heart surgery.

A study of 100 coronary bypass and cardiac valvular surgery patients investigated whether preoperative brain damage, as measured by the Conceptual Level Analogy Test (CLAT), is a major risk factor for postoperative psychiatric symptoms and mortality. Three cognitive psychological tests, including the CLAT, and psychatric interviews were given preoperatively, postoperatively, and at 18-month follow-up. Surgical outcome was specified as: Catastrophic Outcome (death or severe stroke), Psychiatric Complications, or Good Outcome (survival with no psychiatric complications). Inhospital outcome related significantly to analogy test scores, as did both surgical procedure and diagnosis of rheumatic heart disease. However, long-term outcome was unrelated to medical diagnosis and only weakly related to surgical procedure, but highly significantly related to preoperative analogy scores. The CLAT was a more consistent predictor of both short- and long-term outcome than any of the other ten variables considered (medical and surgical variables, inhospital outcome, demographic measures, other psychological tests).

Brain↗
PubMed1975

Psychiatric complications following coronary bypass surgery.

Previous studies of psychiatric complications following open heart surgery have included few if any patients who had coronary bypass surgery. This experiment reports the relative incidence of psychiatric complications in a sample of 97 open heart surgery patients of whom 51 patients (53 per cent) had coronary bypass surgery. The results suggest that the incidence of psychiatric symptoms following coronary bypass surgery is significantly lower (16 per cent) than that following cardiac valvular surgery (41 per cent). Several possible reasons for this large discrepancy in incidence of psychiatric complications are considered.

Age Factors↗