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Biomedical subjects

A Eason

Publications and source records attributed to A Eason.

3 recordsLinked to original sources

Dysphoric interpersonal schemata and preadolescents' sensitization to negative events.

Addresses the hypothesis that interpersonal schemata sensitize dysphoric youngsters to negative social information and contribute to the amplification of depressive symptoms. Sensitization was conceptualized as involving multiple components, including heightened anticipation, selective focus, and rapid information processing. Four studies with separate samples of preadolescents and early adolescents were conducted. Results from 3 laboratory-based studies indicated that depressed and dysphoric youngsters evince relatively negative interpersonal schemata, and that these schemata are related to the 3 components of sensitization. A short-term prospective study examined the hypothesis that dysphoric interpersonal schemata moderate the emotional impact of a normative social stressor, the transition to high school. Results indicated that youngsters who entered the transition with relatively negative schema experienced the transition as more stressful than youngsters with relatively positive schema, and that negative interpersonal schema amplified the effects of stress on depressive symptoms.

Adaptation, Psychological

The proportional decrease in prostate specific antigen level best predicts the duration of survival after hormonal therapy in patients with metastatic carcinoma of the prostate.

OBJECTIVE: To examine the usefulness of a test for prostate specific antigen (PSA) to predict survival in hormonally treated patients with metastatic prostate cancer. PATIENTS AND METHODS: The study comprised 49 patients (mean age 72 years, SD 6) who underwent orchidectomy for metastatic prostate cancer. PSA was measured before orchidectomy and after 6 months, and the absolute, differential and proportional decreases calculated. A Cox proportional hazards regression model, which controlled for patient age, tumour (Gleason) grade and the number of skeletal metastases, was then used to evaluate these estimates of PSA as predictors of survival. RESULTS: The 6-month proportional decrease in PSA from the pre-operative level was the most accurate predictor of patient survival (P = 0.006) after hormonal therapy for metastatic prostate cancer. CONCLUSION: This information may help to direct appropriate patients to new and experimental therapies for metastatic disease.

Aged

Accelerated wound healing of pressure ulcers by pulsed high peak power electromagnetic energy (Diapulse).

The purpose of this study was to evaluate the effect of pulsed high-frequency, high peak power electromagnetic energy (Diapulse) in the healing of pressure ulcers. Patients with Stage II ulcers unhealed within three to 12 weeks and those with Stage III ulcers unhealed within eight to 168 weeks by conventional methods were included in the study. When Diapulse was added to conventional therapy during the nine-month study, all 22 patients healed as evidenced by photographs and measurements of the ulcers. Stage II ulcers healed in one to six weeks (mean 2.33) and all Stage III ulcers healed in one to 22 weeks (mean 8.85). The increased healing time can provide significant cost savings and improved patient care.

Aged