Biomedical subjects

A Ehle

Publications and source records attributed to A Ehle.

4 recordsLinked to original sources

PubMed1985

Evoked potentials in non-convulsive status epilepticus.

To verify the results from previous studies, we performed EPs on 2 patients with nonconvulsive status epilepticus who demonstrated ictal behavioral changes and bilateral, often diffuse electrographic abnormalities. The EP modalities which were used, PVERs, BAERs, and SSERs, are highly reproducible in normal subjects. In contrast to previous findings, the ictal EPs were normal. Our results may indicate that, despite bilateral and frequently generalized ictal activity in some patients with nonconvulsive seizures, sensory processing at the brainstem and visual and somatosensory cortices remains preserved.

Adult↗

PubMed1981

Clinical correlates of midline spikes. An analysis of 21 patients.

Twenty-one children had interictal EEGs showing spikes located at the Fz, Cz, and Pz electrodes; their EEGs were compared with those of age-matched children referred to our laboratory (group 1, 63 children) and children with C3 and C4 spikes (group 2, 41 children). Midline spikes correlated well with a history of seizures (91% vs 73% in group 1 and 76% in group 2) and neurologic abnormality (38% vs 29% in group 1 and 22% in group 2). No patient had progressive neurologic disease or brain tumor. There are two different possible mechanisms in the genesis of midline spikes. In the majority of children, midline spikes may represent generalized epileptiform abnormalities; in a small subgroup, they may be analogous to C3 and C4 spikes and be generated by a cortical epileptogenic focus.

Child↗

PubMed1981

Familial spastic paraplegia, peroneal neuropathy, and crural hypopigmentation: a new neurocutaneous syndrome.

A neurocutaneous syndrome is described in which spastic paraplegia, peroneal neuropathy, and crural hypopigmentation are inherited in a dominant pattern. Spastic paraplegia becomes clinically apparent during adolescence or in childhood and progresses slowly throughout the adult years with a variability in severity of expression. Peroneal neuropathy is documented clinically and by slowing on nerve conduction studies. Pattern-reversal visual evoked potentials also yield a delayed response, but brainstem auditory evoked potentials and somatosensory evoked potentials in upper and lower extremities are normal. Crural hypopigmentation is present in each neurologically affected family member. Although the pattern may vary, a pretibial distribution predominates. The lower-extremity abnormalities of the central and peripheral nervous system and neural crest cell derivatives may share a common relationship, but the abnormal visual evoked potentials suggest a more generalized involvement. This family may represent a transition form between familial spastic paraplegia and the spinocerebellar degenerations.

Adult↗

PubMed1979

Visual evoked potentials in infants with hydrocephalus.

Visual evoked potentials to flash stimuli were recorded in 15 infants with hydrocephalus. All demonstrated increased latencies for the prominent positive component (P2) of the response, compared to the mean value for age-matched controls. In nine infants studied prior to and 1 week after shunt procedure, the P2 latency decreased.

Evoked Potentials↗