Biomedical subjects
Publications and source records attributed to A Ejigou.
A new approach is presented to the study of heterogeneity of the odds ratio in a case-control design when the possible interaction effects are associated with the variables used for multiple matching. This analysis does not require stratification on the matching covariates.
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The matched pairs design is often used in epidemiologic research, both in prospective and retrospective studies. The Kraus estimator of relative risk (1958) has been derived in a number of ways. The development presented here employs an unconditional likelihood function. The estimator is shown to be valid only when disease incidence is low and relative risk is constant over the levels of the covariate. Asymptotic variances are derived.