[Morphological changes of the testis in inguinal hernia].
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Biomedical subjects
Publications and source records attributed to A F Astrakhantsev.
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An experimental study in female rats demonstrated that hyperestrogenemia (unlike hypoestrogenemia or hyperthyroidism) enhanced the myocardial necrotic effect of isoprenaline. There was no clear-cut correlation between the extent of myocardial damage and cAMP phosphodiesterase activity.
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Structural changes and functional features of the testes were studied in 20 patients who had had parotid orchitis (PO) 6 months to 1.5 years before the study. The examination including ultrasonography of the testes, investigation of ejaculate, radioimmunoassay for serum testosterone, FSH, LH brought out a significant reduction of the mean volume and echogenicity of the affected testicles by 44.7 and 50%, respectively, in 15 patients; a 58.2% decrease in the number of spermatozoa in ml; a 71.2% rise in FSH level in 6 patients. Morphometry of biopsy specimen of the testicles on the affected side has shown that mean sectional area of the tubules has diminished by 40%, the spermatogenesis index--by 77.1% while the volume of the intertubular connective tissue increased by 47.7%. Thus, after acute PO, the patients develop atrophic changes in the testes and a decline in spermatogenic function up to secretory infertility.
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