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Biomedical subjects

A F Bliuger

Publications and source records attributed to A F Bliuger.

53 records · Page 3Linked to original sources
PubMedDate not supplied

[Changes in organelle-specific enzyme activity and the ultrastructure of liver cells in cholelithiasis].

Activities of organelle specific enzymes (succinate dehydrogenase, glucose-6-phosphatase, acidic DNAase, acidic RNAase, acidic and alkaline phosphatases) were measured in homogenates and subcellular fractions of liver tissue of patients with cholelithic disease. Liver tissue samples analyzed were investigated also by light and electron microscopy. The data obtained were considered in connection with localization of cholelith in biliary system, type of inflammation, presence of subhepatic cholestasis and of accompanying syndrome of pancreatitis. Typical alterations were observed in the activity of organelle specific enzymes and in the ultrastructure of mitochindria, lysosomes and endoplasmic reticulum in cholelithic disease. The most distinct alterations in the enzymatic activities were found in choledocholithiasis as well as in subhepatic jaundice.

Acid Phosphatase↗
PubMedDate not supplied

[Development of a system for determining antibodies to the surface antigen of the virus of hepatitis B (HBsAb)].

A method for preparation of an immune diagnosticum using human erythrocytes of 0 (I) blood group sensitized with hepatitis B surface antigen in the presence of chromium chloride followed by the addition of formalin solution, for detection of antibody to the hepatitis B surface antigen is described. Using this immune diagnosticum, antibody to the surface antigen of hepatitis B virus was detected in 12-15% of the normal population in the Latvian SSR, and in 91% of patients with hepatitis B.

Antibodies, Viral↗
PubMedDate not supplied

[Intensity of lipid peroxidation and its relation to changes in the composition and antioxidative properties of lipids in acute viral hepatitis].

Interrelationship between the patterns of lipid peroxidation (diene conjugates and the lipid antioxidative activity) and alterations in lipid composition (content of total lipids, phospholipids and cholesterol) was studied in blood serum of patients with acute viral hepatitis and in healthy donors. An increase in content of lipids in blood serum of the patients with the hepatitis but not the intensity of peroxidation reactions in lipids was found to be responsible for the increase in content of the lipid peroxidation products in blood serum. With an increase in severity of the disease relative content of phospholipids in the total lipid fraction as well as antioxidative activity of lipids were elevated, while relative content of cholesterol and level of lipid oxidation were lowered.

Acute Disease↗