PubMed Health⌕ Search

Biomedical subjects

A F Burry

Publications and source records attributed to A F Burry.

35 records · Page 2Linked to original sources
PubMed1977

Cerebellar calcification: a possible marker of lead poisoning.

An unusual form of calcification in the cerebellum has been observed in routine autopsies in Queensland over the past 30 years. In 4 surveys carried out at intervals between 1951 and 1976 the lesion has been found microscopically in 10 to 15% of autopsies. There is a significant correlation between cerebellar calcification and raised lead levels in bone.

Adult↗
PubMed1976

Bilirubin-associated renal papillary necrosis in the homozygous Gunn rat: light-and electron-microscopic observations.

Homozygous members of the mutant Gunn strain of Wistar rats suffer an inherited autosomal recessive deficiency of glucuronyl transferase resulting in unconjugated hyperbilirubinaemia and jaundice. Unconjugated bilirubin visibly accumulated in the interstitium of the renal papillary tip. The deposit is followed by necrosis, first of intersitital cells, loops of Henle and vasa recta and later of collecting ducts. The necrotic, acellular papillary tip eventually separates. Cortical scars correlate with established papillary necrosis. The bilirubin occurs in two ultrastructural forms, crystalline and fibrillar. The deposit is found initially in the interstitium and around but not within basement-membranes. It is accompanied by cytoplasmic adaptive or degenerative changes and loss of cells by desquamation and coagulative necrosis. The lesion can be regarded as a chronic, progressive papillary necrosis similar in its evolution to the papillary necrosis of analgesic nephropathy.

Animals↗
PubMed1976

Calcification in the renal medulla; a classification based on a prospective study of 2261 necropsies.

Kidneys from 1864 necropsies performed in Brisbane, Australia, and from 397 necropsies performed in Christchurch, New Zealand, were examined macroscopically and microscopically. Three zonal and three focal patterns of renal medullary calcification were defined: (1) Outer medullary cortical calcification seen in hypercalcemic conditions. (2) A band of calcification at the boundary of the inner and outer medullar associated with degenerative changes and correlated with aging and arteriolar disease. (3) Calcification concentrated around the loops of Henle in the papilla, sometimes a striking finding in children and common at all ages. Heavy calcification in this region was injurious to the loops. (4) Fine focal calcification in random distribution throughout the medulla. This lesion was seen in virtually all adult necropsies to some degree. (5) Coarse focal deposits in the papillary region, more common in males and in a hotter climate. (6) Randall's plaques also were common in males and in a hotter climate.

Australia↗