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Biomedical subjects

A F Cooper

Publications and source records attributed to A F Cooper.

29 records · Page 2Linked to original sources
PubMed1976

The differentiation of paranoid from affective psychoses by patients' premorbid characteristics.

Various premorbid characteristics of a group of patients aged 50 or over suffering from paranoid psychoses (N = 54) were compared with those of patients of similar age suffering from affective psychoses (N = 57). (The diagnoses were those of the consultants.) The presence of deafness was investigated in the manner described by Cooper et al(1974). Using the discriminant function method, the diagnostic groups were highly significantly differentiated by six independent variables, which in combination predicted 40 per cent of the variance. These were: a 'schizoid personality' factor, the number of surviving children, precipitating events, deafness, family history and social class.

Affective Symptoms↗
PubMed1976

Deafness and psychiatric illness.

Review of the literature concerning the relationship between deafness and psychiatric disorder reveals differences in the pattern of illness depending on the severity of deafness and the age of onset. In particular, the prevalence of schizophrenia in the prelingually deaf is similar to that found in the normal population, whereas the hard of hearing are over-represented among samples of patients suffering from paranoid psychoses in later life. Possible modes of action of long-standing hearing loss in the aetiology of paranoid illnesses are considered: the psychological and social consequences of deafness, the possible contribution of sensory deprivation phenomena, and the interference of hearing loss in attention, perception and communication. Finally, possible future lines of research are suggested.

Age Factors↗
PubMed1976

A comparison of deaf and non-deaf patients with paranoid and affective psychoses.

A comparison was made of the social and domestic background, prepsychotic personality and symptomatology of deaf ('hard of hearing') and non-deaf patients aged 50 or over with paranoid or affective psychoses. The deaf patients were found to be a very heterogeneous group in respect of age of onset, duration, severity and pathological basis of their deafness, but there was a substantial subgroup of paranoid patients with deafness beginning before the age of 45 in whom the personality appeared to have been less deviating than in the remainder. It was thought that the deafness in this subgroup had possibly played a relatively specific role in causing the psychosis. Some problems in identifying deafness and assessing its significance are discussed.

Affective Symptoms↗
PubMed1968

Vitamin D intoxication, with hypernatraemia, potassium and water depletion, and mental depression.

Two elderly patients suffering from manic-depressive psychosis/depressive reaction had concurrently hypercalcaemia from vitamin D intoxication. They developed hypernatraemia with severe potassium and water depletion. Hypercalcaemia was pronounced, but both patients recovered quickly and their depressive symptoms resolved following water and potassium repletion and corticosteroid therapy.

Adrenal Cortex Hormones↗
PubMedDate not supplied

Whose illness is it anyway? Why patient perceptions matter.

Recent studies indicate it is frequently patients' implicit understanding and attitude towards their illness that affect health behaviours such as compliance with medication, follow-up and rehabilitation attendance--important mediators of physical and psychological outcome. An overview of the theory that forms the basis for such findings attempts to explain how illness perceptions mediate health outcome. By examining research which has demonstrated important relationships between illness beliefs and physiological/functional outcome in specific illnesses, this review attempts to bring together psychological theory and clinical outcome measurements; this should demonstrate the value and importance to health-care professionals of considering the patient perception framework.

Attitude to Health↗
PubMedDate not supplied

Acute effects of hormone replacement with tibolone on myocardial ischaemia in women with angina.

This study was designed to evaluate whether hormone replacement therapy with tibolone demonstrated similar effects to those observed with oestrogen on myocardial ischaemia and angina. Ten postmenopausal women with documented coronary artery disease were evaluated by treadmill exercise electrocardiograms before and 24 hours after the oral administration of tibolone 2.5 mg. Onset of myocardial ischemia, as defined by ST segment depression, increased by a median 102 seconds (p = 0.022). Time to onset of angina increased by 31 seconds (p = 0.038), while total exercise time was not significantly affected (p = 0.24). Haemodynamic variables in the form of heart rate, systolic blood pressure and their product were unaffected by tibolone administration. We conclude that tibolone appears to show similar anti-ischaemic properties to oestrogen.

Anabolic Agents↗