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Biomedical subjects

A F Hilton

Publications and source records attributed to A F Hilton.

7 recordsLinked to original sources

Ocular complications in renal transplant patients.

One hundred and seventy-six patients who received a renal transplant between 1982 and 1988 were examined for ocular complications of steroid therapy. Posterior subcapsular cataracts (PSC) were present in 60 patients (34.1%). Patients were classified into three groups (HS, LS, NoS) depending on their maintenance immunosuppression therapy. The HS group received high doses of steroids after renal transplantation. LS had low steroid doses, and NoS had no steroids. The incidence of PSC was 21 of 38 in HS (55.3%), 33 of 117 in LS (28.2%), and 1 of 16 in NoS (6.2%). The difference between HS and LS was statistically significant (chi 2 = 8.1, P < 0.01). Grading the severity of PSC (PSC 0, PSC +, PSC > ++) showed a significant correlation between the degree of PSC and the steroid therapy. In the HS group, five patients had PSC +, and 16 had PSC > ++ (76%), compared to 19 patients with PSC +, 14 patients with PSC > ++ (42%) in the LS group (chi 2 = 4.6; P < 0.05). There was no correlation between the incidence of PSC and use of steroids for more than three months before dialysis. Comparison with the results of our earlier series (1973-1981) using high doses of steroids showed a similar incidence of PSC with HS (40.7% Series 1; 55.3% Series 2) but a lower incidence with LS and NoS.

Adolescent

A family of squints: the differing effects of hypermetropia on four siblings.

Four siblings in a family of five were found to be affected with hypermetropia in differing degrees and with differing effects. These were unilateral hypermetropia, producing amblyopia; hypermetropia inducing an accommodative esotropia with minimal amblyopia and fully controlled with glasses; hypermetropia producing an accommodative esotropia with a high AC/A ratio, fully controlled with bifocals; and hypermetropia producing esotropia which was only partially corrected with glasses, therefore partially accommodative, with a residual squint which required surgery. This family of four nicely demonstrates all the permutations and combinations possible in accommodative-type esotropia and the pitfalls therein.

Accommodation, Ocular

Pre-school vision screening-a pilot study.

The importance of early vision screening in children is well known, but also are the difficulties of choosing a satisfactory programme and its implementation. This paper describes the reasons for the programme being implemented and discusses the method by examination and the co-operation required to carry it out. More than 10,000 children were screened by more than 350 voluntary family doctors. The examinations were carried out throughout Queensland in pre-school centres. The family doctors were fundamental in the success of the programme, as they had the considerable task of examining the children. The scheme was made possible by the co-operation of the family doctors through the help of the Royal Australian College of General Practitioners, The Family Medicine Programme and the Australian Medical Association. These organisations, together with the Division of School Health, Queensland, and The Royal Australian College of Ophthalmologists were responsible for the organisation of the scheme. The results of the Pilot Study and the requirements for an on-going programme are discussed.

Amblyopia

Ocular complications in haemodialysis and renal transplant patients.

115 patients on haemodialysis and 160 renal transplant patients were examined over an eight year period. A high percentage in both groups were found to have ocular complications. These included disorders of the cornea, lens, retina, choroid, and optic nerve. In contrast to other studies on renal transplant patients a relatively large number had symptoms and even required surgery for cataract removal. 65 (40.7%) had posterior sub-capsular cataracts. It is likely that nearly all were caused by the use of prednisone for immunosuppression. Of this number 25 (38.5%) had symptoms and 12 (18.5%) required cataract extraction. Pigmentary disturbances of the retinal pigment epithelium, together with vascular changes in the choroid were found in some. The implication of these relatively unknown complications, together with their possible aetiology, is discussed. The study emphasises the fact that all haemodialysis and renal transplant patients should be monitored for ocular complications.

Adolescent

The diagnosis and management of isolated cyclo vertical muscle palsy.

It is emphasised that isolated Cyclo Vertical Muscle Palsies are more common than is generally realized. Because of this fact they are therefore important. More of these will be uncovered if they are looked for in a sensible manner. A number of conditions can be confused with such a palsy. A differential diagnosis of these conditions is given. A simple and logical method of assessment of such isolated muscle palsies is outlined. Such examination is based on the Parks Three Step Test and the theory behind this has been detailed. Patients each with one of the four possible muscle palsies are discussed. The Management of such conditions is described.

Adult

Scoliosis and vertical ocular muscle paresis.

Patients with a head tilt from a vertical ocular muscle paresis can often be shown to have an accompanying scoliosis. The scoliosis is usually mild and is postural or compensatory. Although this association is quite common, it is very rarely commented upon, because the relationship between the spinal and the ocular problem is little known. It is important because if such a patient presents with a scoliosis, the patient can be spared extensive investigations if the ocular muscle paresis is of long standing and the Orthopaedic surgeon will know he is, most likely, dealing with a mild scoliosis, and one that has a cause. If the ocular muscle paresis is operated upon early enough it may be possible to remove the head tilt and have a good influence upon the scoliosis. Six patients illustrating these points are discussed.

Adult