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Biomedical subjects

A F Jahn

Publications and source records attributed to A F Jahn.

At least 37 records · Page 2Linked to original sources
PubMed1987

Major auricular malformations due to Accutane (isotretinoin).

Vitamin A and vitamin A derivatives have been described as etiologic factors for a number of congenital malformations. Two infants are presented with major auricular malformations including anotia and severe microtia. The infants were products of a pregnancy complicated by Accutane ingestion during the first trimester. Both infants had associated central nervous system malformations. With the increasing use of Accutane for the treatment of cystic acne in young women of child-bearing age, the dangers of teratogenesis in the head and neck area are greatly increased. This presentation will review two such cases as well as give an overview of the embryogenesis and teratogenesis of the auricle.

Abnormalities, Drug-Induced↗
PubMed1987

Tornwaldt's cyst: clinical and radiological aspects.

Tornwaldt's bursae or nasopharyngeal bursae originate at the interface between the embryonic tissue from which the vertebrae develop (the notochord), and the developing foregut. If the opening through which the bursa drains into the nasopharynx becomes obstructed, a Tornwaldt's cyst will develop. The history, clinical and radiological findings and the operative management of a patient with an infected Tornwaldt's cyst are presented.

Adult↗
PubMed1986

Fatal frontal sinusitis due to Neisseria sicca and Eubacterium lentum.

Infectious sinusitis may on occasion be associated with meningitis, subdural empyema, epidural empyema, brain abscess, or osteomyelitis. We report a 29-year-old male patient with frontal sinusitis who developed all of these intracranial complications due to two previously unreported causative organisms, Neisseria sicca and Eubacterium lentum. The fulminant and fatal course resulting from locally invasive disease underscores the importance of early diagnosis and proper treatment of these complications. Possible exacerbating factors in this patient were sickle cell disease and immune compromise due to intravenous drug abuse.

Adult↗
PubMed1984

Medical management of chronic otitis media.

Chronic otitis media can be successfully managed by purposeful and aggressive medical therapy. Frequent and meticulous debridement, topical treatment, and adjunctive systemic antibiotics should be used. Medical treatment is appropriate either as a curative measure, or for preoperative preparation of the ear.

Administration, Topical↗
PubMed1984

Medical management of disorders of swallowing.

Disorders of swallowing in a given patient can result from abnormalities of dentition, the oral cavity (mouth and pharynx), the cricopharyngeal muscle, esophageal skeletal (proximal) or smooth (distal) muscle, the lower esophageal sphincter, and the stomach. Recent advances include refinements in esophageal manometric techniques with reclassification of motility disorders; newer drugs to treat gastroesophageal reflux; recognition of more frequent infections of the esophagus in immunosuppressed patients; and adaptation of the use of medications such as nitrates and calcium-channel blockers, which were previously primarily cardiotonic, for investigative treatment of esophageal motility abnormalities.

Combined Modality Therapy↗
PubMed1981

Osteopetrosis of the temporal bone.

Osteopetrosis is a rare hereditary disorder of bone development. We examined the right temporal bone of a 17-year-old boy with recessive osteopetrosis and a conductive hearing loss and describe the histopathologic characteristics. The conductive deafness in this case was caused primarily by recurrent otitis media.

Adolescent↗
PubMed1981

Velocity of propagation of bone-conducted sound in a human head.

A psychophysical cancellation method after Zwislocki [J. Acoust. Soc. Am. 25, 752-759 (1953)] was used to measure the propagation velocity of bone-conducted sound across the head of an observer. The result, 330 m/s, compares quite well with Zwislocki's earlier value of 260 m/s and Franke's of 300 m/s. Since in all three experiments the velocity was frequency-independent at f greater than 2000. Hz, it is suggested that vibratory energy travels along the flat bones of the cranial vault in the form of plate waves and as distortional waves through its base. [As defined by Cremer and Heckl, Körperschall (Springer, Berlin, 1967), plate waves are but a simpler form of distortional waves.] Quantitatively, the present result appears quite reasonable in the light of the material constants involved and by comparison with other materials.

Bone Conduction↗
PubMed1981

Heredity hearing losses with delayed onset: mechanisms of expression.

Inherited hearing loss with a delayed onset is a feature of an intriguing group of disorders. The mechanisms whereby delayed hearing loss develops may be grouped as primary degenerative (abiotrophic) disorders, secondary degenerative disorders, dysgenerative disorders, and disorders of inappropriate response. Illustrative examples within these four groups are discussed. The difficulties in determining the preclinical latent state in inherited disorders are briefly outlined.

Age Factors↗
PubMed1981

Mendelian genetics and cytogenetics in otolaryngology.

The numerous inherited disorders involving the head and neck are best understood against the background of Mendelian genetics. An appreciation of patterns of inheritance and the factors that modify or simulate then allows the clinician to weigh the importance of family history, to evaluate the basic mechanisms involved in the disorder, and to give advice concerning future generations.

Child↗
PubMed1981

Endaural brain hernia: repair using conchal cartilage.

A case of endaural brain herniation is presented. Reduction of the hernia and repair of the tegmental defect from below was carried out using a plate of conchal cartilage. The entity of endaural brain hernia is briefly viewed, with a discussion of techniques of surgical management. The advantages of otologic repair in suitable cases are listed.

Child↗
PubMed1980

Laryngeal rheumatoid arthritis.

The classic sequence of pathologic changes associated with rheumatoid arthritis as they affect the cricothyroid and cricoarytenoid joints of five larynges is described. Although several previous reports have drawn attention to the presence of rheumatoid arthritis in the larnx, the current study emphasizes that the small joints of the larynx may be involved by the full spectrum of pathologic changes and that both cricothyroid and cricoarytenoid joints are equally prone to the various stages of inflammation, joint destruction and ankylosis that characterize the disease elsewhere. Rheumatoid nodules were seen in two cases and granulomatous areas surrounding cricothyroid joints were noted in two others.

Arthritis, Rheumatoid↗
PubMed1980

Verrucous carcinoma of the nasopharynx--a clinicopathologic case report.

The purpose of this case presentation is to alert the clinician and pathologist to the unique features of verrucous carcinoma. Although the nasopharynx is an unusual site for this tumor, the features inherent to verrucous carcinoma are apparent; a misleadingly benign histologic appearance which contrasts dramatically with the inexorable progressive destruction of normal structures. Secondary infection is common and should not be mistaken for a primary process. Diagnosis rests on dialogue between clinician and pathologist.

Aged↗
PubMed1980

Newer perspectives on the pathology of chronic otitis media.

The application of newer research techniques had led to re-evaluation of the pathology and pathogenesis of chronic suppurative otitis media (CSOM). The infectious-inflammatory process with CSOM and with cholesteatoma is emerging as the major factor responsible for both soft tissue scarring and bone destruction. There is no evidence that pressure plays a role in cholesteatomatous bone resportion. Experimental and clinical evidence favors immigration of external canal skin as the most important mode of cholesteatoma formation. The evidence for attic retraction cholesteatoma is suggestive but less conclusive.

Bacterial Infections↗
PubMed1980

Office myringotomy.

Explore the source record for details and available documents.

Ambulatory Surgical Procedures↗
PubMed1979

Peripheral facial paralysis secondary to metastatic malignant melanoma. A clinicopathologic report.

We report a case of disseminated malignant melanoma in which the initial sign was an isolated peripheral facial palsy on the left side. The cause of the palsy was established five months later, with the appearance of metastatic axillary nodes. The temporal bones demonstrated tumor infiltration within the marrow spaces of the petrous apices bilaterally. The left facial nerve was also extensively involved with melanoma to the level of the geniculate ganglion.

Autopsy↗
PubMed1979

Metastases to the larynx.

Four patients with metastases to the larynx are reported. The pathways of metastatic invasion of the larynx are discussed and illustrated with whole organ laryngeal sections from these cases. Although three of the four cases were clinically silent, all could have been detected on indirect laryngoscopy. The true incidence of laryngeal metastases appears to be much higher than clinically suspected, and indirect laryngoscopy of all patients "at risk" should be considered.

Adult↗