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Biomedical subjects

A F Kaul

Publications and source records attributed to A F Kaul.

5 recordsLinked to original sources

Determining the date of manufacture of drug products from lot numbers.

Information necessary to determine the date of manufacture of many drug products from assigned lot numbers is presented. Eighty-four U.S. drug manufacturers were surveyed by mail. Response was received from 71 (85%) of the companies contacted, but only 34 provided the information necessary to determine the date of manufacture of their drug products from assigned lot numbers. Pharmacists can use this information to remove potentially deteriorated drug products from inventory.

Drug Industry

A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.

Women undergoing abortion by intraamniotic prostaglandin F2alpha were randomized to receive either prochlorperazine edisylate 10mg, hydroxyzine hydrochloride 100mg, or a placebo every four hours by intramuscular injection in a double-blind fashion. Vomiting was significantly more frequent in the placebo-treated group [0.2 +/- 1.5 SD episodes per patient, n=21] than in the groups treated with prochlorperazine [1.2 +/- 0.5 episodes per patient, n=21] or hydroxyzine [0.3 +/- 0.8 episodes per patient, n=19]. The mean number of merperidine injections in the antiemetic-treated groups was lower than in the control group, but this effect was not statistically significant. There was no significant difference between the treated and the control groups in the interval from prostaglandin treatment to abortion.

Abortion, Induced