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Biomedical subjects

A F Nothnagel

Publications and source records attributed to A F Nothnagel.

3 recordsLinked to original sources

Iris varix simulating an iris melanoma.

Iris varix is rare and little is known about its clinical characteristics. We treated a thrombosed iris varix that simulated an iris melanoma. A 53-year-old man developed a dark brown iris mass and hyphema in his left eye. Ultrasound biomicroscopy revealed a circumscribed mass of the iris stroma. Because of suspicion for melanoma, it was removed by sector iridectomy. Histopathologic examination disclosed an extensive focus of stromal hemorrhage, partially surrounded by endothelial cells that showed immunoreactivity to vascular markers. The histopathologic diagnosis was thrombosed iris varix. Iris varix is a rare condition that should be included in the differential diagnosis of iris melanoma.

Diagnosis, Differential↗

Serratia rubidae endophthalmitis following penetrating ocular injury.

A 10-year-old boy incurred penetrating trauma to his left eye by a small piece of wood. Immediate lens aspiration and repair of his corneal laceration were performed. The patient, however, demonstrated "persistent severe uveitis." On the fourth day following his injury, an uncomplicated pars plana vitrectomy was performed in combination with intracameral injection of gentamicin, cefazolin, and dexamethasone. Cultures of the vitrectomy specimen demonstrated Serratia rubidae. Postvitrectomy treatment with parenteral gentamicin, cefazolin, prednisone, and oral trimethoprimsulfamethoxazole resulted in a complete cure of the endophthalmitis and retention of good visual function. This patient represents the first reported case of Serratia rubidae endophthalmitis.

Bacterial Infections↗